brucellosis

Question 1

Brucellosis (malta fever)
mechanism of transmission

Answer 1

• consumption of infected ,unpasteurized animal products

*contact of skin or mucous membrane with infected animal tissue (placenta..), blood milk urine

• inhalation of infected aerosolized particles

Question 2

Brucellosis signs and symptoms

Answer 2

*fever * malaise * night swats *arthralgia (musculoskeletal ) *hepatomegaly *splenomegaly
* osteomyelitis more common at the cervical spine than lumbar

Question 3

Brucellosis laboratory findings

Answer 3

• elevated alanine aminotransferase
  *mild anemia *leukopenia *leukocytosis *relative leukocytosis * thrombocytopenia *pancytopenia

Question 4

Brucellosis tx:
adult males

Answer 4

doxycycline+ streptomycin

Question 5

Brucellosis tx: nonpregnant adult

Answer 5

doxycycline +gentamicin

Question 6

Brucellosis tx: children >6yo

Answer 6

doxycycline + rifampin

Question 7

Brucellosis tx: children < 6yo and pregnant woman

Answer 7

TMP-SMX + rifampin

Question 8

Brucellosis incubation period

Answer 8

from one week to several months
with symptoms appearing suddenly or gradually

Question 9

primary goal of brucellosis treatment is

Answer 9

address current infection and prevent relapses

Question 10

Brucellosis tx period of time

Answer 10

in nonfocal Brucellosis in adults involves 6 weeks course with at least two antimicrobial agents ,typically IM streptomycin+ doxycycline