brs endocrine Flashcards

0
Q

A woman has hypocalcemia, hyperphosphatemia, and decreased urinary phosphate excretion. Injection of parathyroid hormone (PTH) causes an increase in urinary cyclic adenosine monophosphate (cAMP). The most likely diagnosis?

A

hypoparathyroidism after thyroid surgery

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1
Q

What hormone acts on its target tissues by a steroid hormone mechanism of action?

A

Thyroid hormone

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2
Q

A man who has galactorrhea is found to have a prolactinoma. His physician treats him with bromocriptine, which eliminates the galactorrhea. The basis for the therapeutic action of bromocriptine is that it

A

inhibits prolactin release from the anterior pituitary

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3
Q

What function of the Sertoli cells mediates negative feedback control of FSH secretion?

A

synthesis of inhibin

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4
Q

What hormone is derived from proopiomelanocortin (POMC)?

A

Adrenocorticotropic hormone (ACTH)

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5
Q

What inhibits the secretion of growth hormone by the anterior pituitary?

A

somatomedins

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6
Q

Selective destruction of the zona glomerulosa of the adrenal cortex would produce a deficiency in which hormone ?

A

Aldosterone

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7
Q

What explains the suppression of lactation during pregnancy?

A

blood levels of estrogen and progesterone are high

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8
Q

What results from the action of parathyroid hormone (PTH) on the renal tubule?

A

stimulation of Ca++ reabsorption in the distal tubule

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9
Q

A woman has hirsutism, hyperglycemia, obesity, muscle wasting, and increased circulating levels of ACTH. The most likely cause of her symptoms is

A

primary overproduction of ACTH (Cushing’s disease)

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10
Q

This disease decreases the conversion of 25-hydroxycholecalciderol to 1,25-dihydroxycholecalciferol?

A

Chronic renal failure

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11
Q

Increased ACTH secretion would be expected in patients with

A

chronic adrenocortical insufficiency (Addison’s disease)

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12
Q

What would expected to be increased in a patient with Grave’s disease

A

triiodothyronine (T3) levels

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13
Q

secretion of oxytocin is increased by

A

dilation of the cervix

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14
Q

what hormone acts by an inositol 1,4,5-triphosphate (IP3)-Ca++ mechanism of action?

A

GnRH

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15
Q

A patient with untreated diabetes type I is brought to the ER. An injection of insulin would be expected to cause an increase in her

A

blood pH

16
Q

The source of estrogen during the second and third trimesters of pregnancy is the

A

fetal adrenal gland, fetal liver, and placenta

17
Q

What causes increased aldosterone secretion

A

decreased blood volume