brs endocrine Flashcards
A woman has hypocalcemia, hyperphosphatemia, and decreased urinary phosphate excretion. Injection of parathyroid hormone (PTH) causes an increase in urinary cyclic adenosine monophosphate (cAMP). The most likely diagnosis?
hypoparathyroidism after thyroid surgery
What hormone acts on its target tissues by a steroid hormone mechanism of action?
Thyroid hormone
A man who has galactorrhea is found to have a prolactinoma. His physician treats him with bromocriptine, which eliminates the galactorrhea. The basis for the therapeutic action of bromocriptine is that it
inhibits prolactin release from the anterior pituitary
What function of the Sertoli cells mediates negative feedback control of FSH secretion?
synthesis of inhibin
What hormone is derived from proopiomelanocortin (POMC)?
Adrenocorticotropic hormone (ACTH)
What inhibits the secretion of growth hormone by the anterior pituitary?
somatomedins
Selective destruction of the zona glomerulosa of the adrenal cortex would produce a deficiency in which hormone ?
Aldosterone
What explains the suppression of lactation during pregnancy?
blood levels of estrogen and progesterone are high
What results from the action of parathyroid hormone (PTH) on the renal tubule?
stimulation of Ca++ reabsorption in the distal tubule
A woman has hirsutism, hyperglycemia, obesity, muscle wasting, and increased circulating levels of ACTH. The most likely cause of her symptoms is
primary overproduction of ACTH (Cushing’s disease)
This disease decreases the conversion of 25-hydroxycholecalciderol to 1,25-dihydroxycholecalciferol?
Chronic renal failure
Increased ACTH secretion would be expected in patients with
chronic adrenocortical insufficiency (Addison’s disease)
What would expected to be increased in a patient with Grave’s disease
triiodothyronine (T3) levels
secretion of oxytocin is increased by
dilation of the cervix
what hormone acts by an inositol 1,4,5-triphosphate (IP3)-Ca++ mechanism of action?
GnRH