Bronchodilators: Adrenergics (SABA & LABA), Methylxanthines, & Anticholinergics (SAMA & LAMA)

Question 1

three types of bronchodilators

Answer 1

beta adrenergics
methylxanthines
anticholinergics

Question 2

three types of beta adrenergics

Answer 2

short acting (SABA)
long acting (LABA)
oral

Question 3

which adrenergic is used for quick relief of asthma attack

Answer 3

SABA

Question 4

which drug class, SABA or LABA, has more adverse effects?

Answer 4

SABAs

Question 5

albuterol and levalbutrol belong to what class? which one is the prototype?

Answer 5

SABA

albuterol

Question 6

take this drug class PRN to abort an ongoing attack or prevent EIB

Answer 6

SABA

Question 7

adverse effects include GI upset, tremors, nervousness, tachycardia, and heart palpitations for which drug class

Answer 7

SABAs

Question 8

which drug class is preferred for patients with stable COPD?

Answer 8

LABAs

Question 9

arformoterol, formoterol, indacaterol, and salmeterol belong to what drug class? which one is the prototype?

Answer 9

LABAs

salmeterol

Question 10

which drug class is used for chronic maintenance of asthma & COPD + prevention of EIB, usually in combination to control asthma symptoms

Answer 10

LABAs

Question 11

which drug class is contraindicated to use alone in asthma

Answer 11

LABAs

Question 12

what must LABAs be combined with?

Answer 12

inhaled glucocorticoid

Question 13

what can salmeterol be combined with in between doses if supplemental bronchodilation is needed?

Answer 13

SABA

Question 14

theophylline is the prototype for which drug class?

Answer 14

methylxanthines

Question 15

therapeutic index for theophylline

Answer 15

5-15

> 20 is toxic

Question 16

this drug used to be first line for COPD, but is no longer due to side effects

Answer 16

theophylline

Question 17

this drug is used for mainetance therapy for chronic stable asthma

Answer 17

theophylline

Question 18

smoking can decrease the levels of this drug, requiring some patients to increase their dose by up to 50%

Answer 18

theophylline

Question 19

caffeine, smoking, beta blockers, dig, and lithium interact with this drug

Answer 19

theophylline

Question 20

Anticholinergics:
SAMA prototype =
LAMA prototype =

Answer 20

SAMA = ipratropium
LAMA = tiotropium

Question 21

which anticholinergic prevents bronchoconstriction?

Answer 21

ipratropium

Question 22

which drug class may cause paradoxical bronchospasm? how do you avoid it?

Answer 22

anticholinergics

prime new MDI with 2 sprays prior to first use