Bronchodilators: Adrenergics (SABA & LABA), Methylxanthines, & Anticholinergics (SAMA & LAMA) Flashcards
three types of bronchodilators
beta adrenergics
methylxanthines
anticholinergics
three types of beta adrenergics
short acting (SABA) long acting (LABA) oral
which adrenergic is used for quick relief of asthma attack
SABA
which drug class, SABA or LABA, has more adverse effects?
SABAs
albuterol and levalbutrol belong to what class? which one is the prototype?
SABA
albuterol
take this drug class PRN to abort an ongoing attack or prevent EIB
SABA
adverse effects include GI upset, tremors, nervousness, tachycardia, and heart palpitations for which drug class
SABAs
which drug class is preferred for patients with stable COPD?
LABAs
arformoterol, formoterol, indacaterol, and salmeterol belong to what drug class? which one is the prototype?
LABAs
salmeterol
which drug class is used for chronic maintenance of asthma & COPD + prevention of EIB, usually in combination to control asthma symptoms
LABAs
which drug class is contraindicated to use alone in asthma
LABAs
what must LABAs be combined with?
inhaled glucocorticoid
what can salmeterol be combined with in between doses if supplemental bronchodilation is needed?
SABA
theophylline is the prototype for which drug class?
methylxanthines
therapeutic index for theophylline
5-15
> 20 is toxic
this drug used to be first line for COPD, but is no longer due to side effects
theophylline
this drug is used for mainetance therapy for chronic stable asthma
theophylline
smoking can decrease the levels of this drug, requiring some patients to increase their dose by up to 50%
theophylline
caffeine, smoking, beta blockers, dig, and lithium interact with this drug
theophylline
Anticholinergics:
SAMA prototype =
LAMA prototype =
SAMA = ipratropium LAMA = tiotropium
which anticholinergic prevents bronchoconstriction?
ipratropium
which drug class may cause paradoxical bronchospasm? how do you avoid it?
anticholinergics
prime new MDI with 2 sprays prior to first use