Bronchiectasis Flashcards

1
Q

What is bronchiectasis?

A
  • localised, irreversible dilation of the bronchial tree
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2
Q

How would a patient with bronchiectasis present?

A
  • recurrent ‘chest infections’
  • recurrent antibiotic prescriptions
  • no response to antibiotics
  • short lived response to antibiotics
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3
Q

What is the effect of bronchiectasis on the airways?

A
  • dilation of airways, thickening of bronchial walls, lock of tapering of the airways
  • in bronchiectasis the accompanying blood vessel is smaller than its bronchiole
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4
Q

How is bronchiectasis treated?

A
  • stop smoking
  • flu vaccine
  • pneumococcal vaccine
  • reactive antibiotics: send sputum sample, give antibiotics appropriate to most recent positive culture
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5
Q

How is bronchiectasis treated when the patient is colonised with persistent bacteria?

A
  • oral macrolide antibiotic
  • nebuliser gentamicin, colomycin
  • pulsed IV abx
  • alternating oral antibiotics
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6
Q

Describe the anti inflammatory treatment of bronchiectasis?

A
  • low dose macrolide antibiotics reduces exacerbations
  • clarithromycin 250mg 1/day
  • azithromycin 250mg 3/week
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7
Q

How are acute exacerbations of bronchiectasis treated?

A
  • 2 weeks of antibiotics appropriate to most recent positive sputum sample
  • send sputum every time
  • aggressively eradicate pseudomonas aeriginosa
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