Bronchial carcinoma Flashcards

1
Q

General features of cancer

A
  1. malignant tumour
  2. uncontrolled replication
  3. local invasion
  4. metastases (lymphatic spread, blood stream, serous cavity)
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2
Q

risk factors

A
  1. smoking
  2. asbestos
  3. radiation
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3
Q

symptoms

A
  1. cough
  2. haemoptysis
  3. dyspnoea
  4. chest pain
  5. recurrent/ slowly resolving pneumonia
  6. lethargy
  7. weight loss
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4
Q

signs

A
  1. cachexia
  2. anaemia
  3. clubbing
  4. supraclavicular nodes
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5
Q

features of small cell

A
  1. rapidly progressive disease
  2. early metastases
  3. rarely suitable for surgery
  4. good initial response to chemo
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6
Q

non-small cell

A
  1. includes squamous + adenocarcinomas
  2. surgery or radical radiotherapy
  3. less response to chemo
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7
Q

Metastases places

A
  1. liver
  2. brain
  3. bone
  4. adrenal
  5. skin
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8
Q

complications

A

Local:

  1. recurrent laryngeal nerve palsy
  2. phrenic nerve palsy
  3. rib erosion
  4. pericarditis
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9
Q

CXR

A

peripheral nodule, consolidation, lung collapse, pleural effusion

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10
Q

CT and PET scan

A

stage tumour

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11
Q

bronchoscopy

A

give histology and assess operability

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12
Q

other tests

A

FBC, spirometry. endobronchial ultrasound (EBUS)

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13
Q

Radiotherapy

A

small cell - used for bronchial obstruction, SVC obstruction, haemoptysis, bone pain and cerebral metastases

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14
Q

endobronchial therapy

A

small cell - stent insertion for stridor, photodynamic therapy, laser

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15
Q

pleural drainage

A

small cell - pleural effusions

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16
Q

surgery

A

non small cell

17
Q

curative radiotherapy

A

non small cell

18
Q

chemo and/or radiotherapy

A

non small cell

19
Q

contraindications of surgery

A
  1. SVC obstruction

2. FEV