Brief Intro To Immune system Flashcards
What is the progenitor to all immune cells?
Hematopoietic stem cells (HSCs)
HSCs give rise to what linneages?
Lymphoid and myeloid
Lymphoid linneage gives rise to what cells?
- B-cells (memory and plasma)
- T-cells (memory, cytotoxic and helper)
Myeloid linneage gives rise to what immune cells?
- monocytes (dendritic cells or macrophages)
- mast cells
- Basophils
What is complement innate immunity?
Direct interaction and lysis of pathogens
What is phagocytosis?
The engulfing of pathogens by macrophages- interaction with cytokines and interferons allows for antigen presentation
What is the dendritic cell?
An antigen presenting cell, causes the release of cytokines and interferons causong activation in the innate and adaptive immune systems.
Whats the job of a T-helper cell?
T-helper binds to antigens present in dendritic cell. Activates B-cells and T-cells
What are NK cells?
Cells that belong to innate and adaptive immine system. Produce interferons.
Innate immunity is….
Fast and non-specific
Adaptove immunity is….
Long term and specific
Innate immunity route?
Infection,recognition of pathogen,Activation of cells+inflammation, removal of infectious agent.
Adaptive immunity route?
Infection, stimulation of T+B cells, expansion and training of T+B cells, migration to effected site, removal of infectious agent.
