Brian Plasticity 2 Flashcards
Brains response to experience
Communication of cells through synapse
Learning
Memory
Bilateral medial temporal lobectomy
H.M was an epileptic who , in 1953 at the age of 27 had his medial temporal lobes removed
Seizures dramatically reduced - but so was memory
Amnesia
Amnesia
Retrograde (backward acting) unable
To remember past
Anterograde - unable to form new memories
While HM - unable to form long term memories , his STM was intact
Assessing H.M
Digit span - repeat long digits as time between learning and recall was within the duration of STM
Block Tapping memory span test - this test demonstrated that HM amnesia was global
Mirror drawing task - exhibited improvement with practice - able
To show memory skills
Contributions of HM case
Medial temporal lobes involved in memory
STM & LTM separate - memory consolidation problem
Memory may exist but not recalled
Explicit , conscious memory - knowing what
Implicit unconscious memory - knowing how
Medial temporal lobe amnesia
Not everyone with this form of amnesia are unable form new explicit long term memories Semantic memory (gen info) Episodic memory (events experienced) may not functionally normally
Hippocampus and Consolidation
HM has some retrograde amnesia
Perhaps hippocampus stores memories temp in order to consolidate
Object-Recognition Memory
Early animal models of amnesia involved implicit memory and assumed the hippocampus was key
1970- monkeys with bilateral temporal lobectomy we show LTM deficits
Like HM performance was normal when memory needed
Object recognition deficits and medial temporal lobectomy
Bilateral removal of the rhinal cortex results in object - recognition deficits
Removal of hippocampus produces moderate effects on object recognition
Removal of the amygdala has no effect on object recognition
Hippocampus
Rhinal cortex - object recognition
Hippocampus for spatial location
Cognitive map theory
Constructs and stores allocentric maps of the world
Configural association theory
- involved in retaining the behaviour significance of combinations of stimuli
Where are memories stores?
Hippocampus - limbic system , integral to spatial navigation and long term memory function
Amygdala - mass of grey matter located in anterior medial proportion of temporal lobe - to form and store memories associated with emotional events
Basal ganglia
Collections of nuclei found in medial temporal lobe - unconscious memory process like motor skills , locomotion and implicit memory
Frontal lobes
Located at front of each hemisphere , linked to coordination of info and working memory, also play role in remembering events in future aswell well as upcoming