breast stuff missed Flashcards
triple assessment include
clinical
imaging - mammogram + US
pathology - US guided core biopsy
what is the secretory cell in breast
acini
what cells in the breast contract to eject milk
myoepithelial
benign breast tumours
phyllodes tumour
intraductal papilloma
non neopastic breast diseases
gynaecomastia fibrcystic change hamartoma fibroadenoma scelrosing lesion
what drugs can cause fat necrosis of breast
warfarin
leaf tumour
phyllodes
what type of carcinomas are breast carcinomas
adenocarcinomas
types of breast carcinoma
ductal and lobular
precursor lesions to lobular neoplasia
atypical lobular hyperplasia
lobular carcinoma in situ
features of lobular neoplasia
multifocal and bilateral
not palpable - incidental finding
may calcify - seen on mammogram
what is pagets disease of the nipple
high grade DCIS oxtending down duct to nipple . still an in situ carcnoma
management of DCIS
surgery
adjuvant XRT
chemoprevention
what identifies an invasive breast carcinoma
has broken through basement membrane with poss metastesis
give examples of anti oestrogen therapy
oophrectomy
tamoxifen ( OE receptor antag )
aromatase inhibitors -letrozole
GnRH analogues - goserelin