breast pathology

Question 1

describe the staging of FNA

Answer 1

C1- unsatisfactory 
C2 - Benign 
C3- atypia probs benign 
C4 - sus of malignancy 
C5 - malignant

Question 2

describe the staging system of core needle biopsy

Answer 2

same as for FNA except B5a -carcinoma in situ and B5b invasive carcinoma

Question 3

what age group is most likely to get fibrocystic change? what abnormalities are seen

Answer 3

women aged 20-50

menstural abnormalities eg early menarche or late menopause often resolves after menopause

Question 4

cobblestone appearance

Answer 4

fibrocystic change

Question 5

blue domed with pale fluid

Answer 5

fibrocystic change

Question 6

how do fibrocystic change present

Answer 6

asymp or smooth discrete breast lump
sudden or cyclical pain
lumpiness

Question 7

what do fibrocystic change look like microscopically

Answer 7

apocrine epithelium anf thin with fibrotic wall

Question 8

what is a hamartoma

Answer 8

circumsied lesion containing all cell types norm to breast but in abnorm proportion

Question 9

rubber, grey/white ?

Answer 9

fibroadenoma

Question 10

what age does fibroadenoma peak

Answer 10

in 20s

Question 11

mouse lesion

Answer 11

fibroadenoma

Question 12

how does fibroadenoma present

Answer 12

painless, firm , discrete , mobile mass

Question 13

treatment of fibroadenoma

Answer 13

reassure, excise if wanted

Question 14

benign disorderly proliferation of acini and stroma

Answer 14

sclerosing lesion

Question 15

types of sclerosing lesions

Answer 15

sclerosing adenosis and radial scar

Question 16

describe sclerosing adenosis

Answer 16

aymp or pain tenderness or lumpiness/thickness

age 20-70 often with other breast changes

Question 17

stellate architecture and central puckering

Answer 17

radial scar

Question 18

describe symptoms of duct ectasia

Answer 18

pain, episodic inflam , bloody /purulent discharge , fistulation or nipple retraction

Question 19

risk factor for duct ectasia

Answer 19

smoking

Question 20

what is the most ompirtant adjunctive imaging in breast cancer

Answer 20

us

Question 21

what breast carcinoma is ultrasouns not sensitive for

Answer 21

ductal carcinoma in situ

Question 22

what is the better neo- adjunctive treatment to achieve breast conservation out of aromatase inhibitors or tamoxifen (OE antag )

Answer 22

aromatase inhibitors