Breast Pathologies Flashcards

1
Q

What is the most common benign condition of the breast?

A

fibrocystic breasts

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2
Q

Triple negative breast cancer means…

A

no estrogen receptors
no progesterone receptors
no human epidermal growth factor receptor 2 (HER2)

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3
Q

A radical mastectomy involves…

A

removal of the breast, pectoralis muscles, chest fascia & same-side lymph nodes

also followed by chemo & radiation

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4
Q

A modified radical mastectomy involves…

A

removal of breast, chest fascia, lymph nodes, but pectoral muscles are left in tact

chemo and radiation may be required - still a common surgery

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5
Q

A simple mastectomy involves…

A

removal of the breast, but lymphatics and pectoral muscles are preserved

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6
Q

A lumpectomy involves…

A

excision of the mass itself and some adjacent tissues

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7
Q

What is a quadrectomy?

A

surgical procedure where affected quadrant of breast is removed - M/C with stage 1 & 2 cancers. may also remove some lymph nodes and skin.

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8
Q

What are the only structural supports in the breast?

A

Cooper’s ligaments (fascial structures)

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9
Q

What is found in the retromammary space (relevant to tx goals)?

A

a channel of lymph drainage from the breast that is easily compressed

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10
Q

75% of lymph drains from the breast into the ____ and 25% drains where else?

A

axillary

25% goes superiorly, to the other breast, and downward/laterally

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11
Q

True or false: cells of breast tissue are not controlled by the nervous system

A

true, they are hormonally controlled

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12
Q

What are Rotter’s nodes?

A

small lymph nodes between the pec major & minor muscles

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13
Q

Organs that refer pain to the breast include…

A

angina/heart pain
gall bladder
esophagus

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14
Q

Define “retromammary space”

A

loose areolar c.t. separating the breast from the pec major muscles - often site of breast implantation!

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15
Q

Though different in every person, describe the passage of breast lymph OTHER than via the axilla?

A

internal mammary chain (adjacent to sternum) > rectus abdominus lymphatics > subdiaphragmatic nodes > intercostal spaces > posterior paravertebral nodes

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16
Q

What defines true gynecomastia?

A

enlargement of the breast’s glandular tissues, not just excess fat

17
Q

What is Klinefelter syndrome?

A

XXY

18
Q

A major goal of prostate cancer tx is to reduce ____ levels, primarily achieved by either:

A

drug therapy or surgical removal of the testicles

19
Q

unfinished

A