Breast disease Flashcards
What are the types of benign breast lesions ?
1) nonproliferative,
2) proliferative without atypia
(sometimes referred to as “fibrocystic changes”)
3) atypical hyperplasia.
__________is another type of nonmalignant breast lesion that is noteworthy because it is associated with a significantly increased risk of future development of breast cancer
Lobular carcinoma in situ
What is the most common type of non-proliferative breast lesion?
Simple breast cyst seen b/w the age of 35-55.
_______ is a benign proliferative condition of the terminal duct lobular units characterized by an increased number of _____and their _____.
Sclerosing adenosis,
Acini and their glands
Florid hyperplasia and sclerosing adenosis are conditions with what risk of breast cancer ?
They are proliferative lesions without atypia and have small to moderate risk.
What is the location and presentation of intraductal papilomas ?
These are tumours of the lactiferous duct that may be solitary and centrally located or may be multiple and peripherally located and often presents with nipple discharges. They are usually seen in woman b/w the age of 30-50 and are not usually associated to cancer.
The risk of breast cancer in those with atypical hyperplasia is about ______ higher than in those who don’t have atypical hyperplasia
four times
_________, which consist of benign glandular cells with minimal stromal elements, can present as a breast mass or may be seen on routine breast imaging
Tubular adenomas
What is Phyllodus tumour ?
Phyllodes tumors are rare fibroepithelial tumors that account for 0.3–0.5% of female breast tumors, the peak of which occurs in women between the ages of 45 and 49 years that are capable of a diverse range of biologic behaviors. In their least aggressive form, phyllodes tumors behave like benign fibroadenomas, although with a propensity to recur locally.
what is lobular carcinoma in situ?
Lobular carcinoma in situ (LCIS) is an uncommon condition in which abnormal cells form in the milk glands (lobules) in the breast. Lobular carcinoma in situ (LCIS) isn’t cancer. But being diagnosed with LCIS indicates that you have an increased risk of developing breast cancer.
Women diagnosed with LCIS have About a ___ chance of developing ductal carcinoma in situ (DCIS) or invasive breast cancer in 10 years. About a ___ chance of developing DCIS or invasive breast cancer in 20 years.
10%, 20%
Unilateral, uniductal and spontaneous ______carries a higher risk of malignancy and should be further evaluated with ultrasound.
Nipple discharges.
What are the 3 types of mastalgias ?
Cyclical, non-cyclical and extra-mammary.
What are the causes of cyclic mastalgia ?
Menstruation, contraceptives, and ovulation induction therapy.
What are the causes of non-cyclic mastalgia ?
mastitis, trauma, thrombophlebitis (Mondor disease), cysts, tumors, and cancer.
