Breast conditions Flashcards
1
Q
3 aetiological factors for breast ca
A
1 hormonal
2 genetic
3 environmental
2
Q
Describe the mutations in breast cancer
A
- Increased HER2/NEU
- Increased RAS/MYC
- Decreased BRCA1 (50%) + BRCA2 (30%)
3
Q
Receptor status of lobular cancer?
A
ER/PR negative, HER2/neu positive, E-cadherin negative