Breast conditions Flashcards by Emily Zdilar | Brainscape

Q

3 aetiological factors for breast ca

A

1 hormonal
2 genetic
3 environmental

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Q

Describe the mutations in breast cancer

A

Increased HER2/NEU
Increased RAS/MYC
Decreased BRCA1 (50%) + BRCA2 (30%)

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Q

Receptor status of lobular cancer?

A

ER/PR negative, HER2/neu positive, E-cadherin negative

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