Breast Cancer Flashcards
name the blood supply of the breast?
axillary artery & vein
Internal mammary artery & vein
Intercostal arteries & veins
what hormones do the breast produce?
oestrogen- external appearance
protgesterone - pepares mammary glands for milk
epidemiology and aetiology of breast cancer
most common cancer in the UK mostly in 50yrs + late child birth age late menopause 5%> alcohol high hormone levels hereditry - 4+ relatives = high risk
describe the spread of cancer cells via the lymph nodes in the breast
axillary lymph nodes level 1,2,3,
supraclavicular nodes
internal mammary nodes
signs and symptoms of breast cancer
nipple retraction. lympoedema, lump, mainly painless, skin ulceration, sore
breast investigations?
ultrasound screening mammogram biopsy palpatation x-ray senital node biopsy MRI
what surgery options are available ?
mastectomy
lumpectomy
breast conserving surgery - wide local excision or quadrantectomy
axillary surgery - lymphodoema
identify staging of T1-T2, T4a-T4b
T1 - tumour less than 2cm T2 - 2cm-5cm T3 - 5cm + T4a - invasion of chestwall T4b -ulceration
describe adjvant HORMONE used for breast cancer?
premenopausal - 5yrs TAMOXIFEN
post menopausal - aromatase inhibitors
when is chemo mostly used?
patients undewr 50yrs
6 cycles every 21days
given before RT or during
side effects of RT in breast cancer
cosmesis shoulder dsyfunction (surgery) fibrosis cardiac morbidity cough
