breast cancer Flashcards
1
Q
what percent of breast cancer is HER2 positive?
A
25-30%
2
Q
what 2 oral agents target HER2 and EGFR positive breast cancer?
A
lapatinib and neratinib. Neratinib also targets the HER4 pathway
3
Q
name 3 IV HER2 inhibitors. Which is also indicated for gastric cancer?
A
trastuzumab, pertuzumab, and ado-trastuzumab emtansine. trastuzumab is also indicated for gastric or gastroesophageal junction cancer
