Breast Anatomy Flashcards

1
Q

What are breasts?#

What are they made up of?

A

Modified and highly specialised sweat glands that are depndent on hormones. They experience physiological changes with age and pregnancy

They are comprised of glandular epithelial tissue made up of ducts and lobules as well as mesenchymal fat and fibrous tissues

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2
Q

Describe the ultrastructure of breasts?

A

Each breast has 8-10 lobules arranged like the petals of a flower. inside each lobe are many smaller structures called lobules. At the end of each lobule are tiny sacs(bulbs) that can produce milk

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3
Q

What are the boundaries of the breasts

A

They extend from the 2nd or 3rd rib down to the 6th rib.

They range from the sternal edge to the mid-axillary line.

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4
Q

How are breasts related to the chest wall

A

2/3rds lie upon the deep pectoral fascia.

1/3rd lie upon fascia covering the serratus anterior

They are all anchored to the dermis by the suspension ligament of Cooper

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5
Q

Explain the anatomy of the breast

A

Nipple+ Areola –> lactiferous duct–> parenchyma

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6
Q

Describe the structure of the nipple

A

Contains no fat or hair
Contains collagenous dense connective tissue, elastic fibres and bands of smooth muscle
The tips of the nipples are fissured with lactiferous ducts

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7
Q

Describe the structure of the Areola

A

The areola is the skin around the nipple
Contains multiple sweat and sebacious glands
Produce oily lubricant to provide protection to the nipple and areola

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8
Q

How is the breast divided?

A

4 quadrants:

Upper lateral quadrant- superolateral quadrant- contains axillary tail
Upper medial quadrant- superomedial quadrant
Lower lateral quadrant- inferolateral quadrant
Lower medial quadrant- inferomedial quadrant

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9
Q

What is the breast like in males?

When does the breast change in males?

A

Rudimentary. It is formed by two small duct without lobules or alveoli. There is little supporting fibroadipose tissue.

There is temporary enlargment in the newborn and during puberty

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10
Q

How do the breast develop?

A

Mammary crests develop during the 4th week of gestation. These breast extend from the axillary region to the inguinal region.

Primary mammary buds become secondary buds which become lactiferous ducts which branch

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11
Q

What are the breasts supplied by?

Name some of the major branches

A

Iliary artery, internal thoracic artery and some intercostal arteries.

Thoracoacromial artery- branch of axillary artery
Lateral thoracic artery- more posterior branch of axilla
Internal mammary (thoracic artery)- branch of subclavian

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12
Q

What innervates the breast?

A

The anterior and lateral cutaneous branches of the 4-6th intercostal nerves convey sensing fibres to the skin of the breast. They also carry sympathetic fibres or the blood vessels to the smooth muscle around the breast

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13
Q

How do the breast drain lymphatically

A

75% of the breasts lymphatic drainage in the lateral quadrants goes into the axillary lymph nodes. Some lymphs may drain directly into the supraclavicular or inferior cervical nodes. Lymphs from medial quarters drain to the parasternal or to the opposite breast

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14
Q

Describe the soft tissue of the breast?

A

Made up of lobes which contain a network of glandular tissue consisting of branching ducts and secretory lobules in a connective tissue stroma.
The terminal duct lobular unit is the functional milk secretory component of the breast

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15
Q

Describe the connective tissue of the breast

A

The connective tissue stroma that surrounds the lobules is a dense and fibrocollagenous whereas the intra lobular tissue has a loose texture

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16
Q

How does the histology of a breast appear

A

Extensive branching system (purple) which is surrounded by dense fibrous interlobular tissue (pink) and adipose tissue (white). Ducts and acini are lined by luminal epithelial cells (columnar purple) and myoepthelial cells (circular purple)

17
Q

Describe the structure of breast before puberty

A

Breasts contain lactiferous duct but no alveoli. Until puberty little branching occurs, before puberty breasts in both sexes contain ducts.

They have a varying degree of branching with no lobules

18
Q

Describe the structure of breasts during puberty

A

In response to hormones the ducts start branching posteriorly.

There are solid masses of glandular polyhedral cells (alveoli) and an accumulation of lipids in the adipocytes.

19
Q

Describe the structure of breasts during pregnancy

A

Enlarged lobules, dilated acini, epithelium may be columnar or cuboidal

20
Q

Describe the structure of breasts postmenopause

A

There is a progressive atrophy of lobules and ducts. A fatty replacement of glandular tissue

21
Q

What is gynecomastia-

What is athelia-

What is amastia

A

Postnatal development of the lactiferous ducts, hyperplasia of the breasts occur during puberty

Lack of nipple

Lack of breast

22
Q

What is polymastia

What is polythelia

What is a fibrocystic chnage in the breast

A

Extra breast

Extra nipple

Can range from fibrosis, cysts, apocrine metaplasia, ductal epithelial hyperplasia

23
Q

What is meant by fat necrosis of the breast?

What is duct ectasia?

A

A lesion caused by trauma, may stimulate carcinoma both in clinical changes and in changes picked up on a mammogram. They contain histocytres with foamy cytoplasm. They are lipid filled cycts

A blockage in the breast duct