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Surgery > Breast > Flashcards

Breast Flashcards

1
Q

Incidence of breast cancer in India

A

1 in 21 women

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2
Q

R/F for breast cancer

A
  1. Age
  2. Early menarche & late menopause
  3. Family history
  4. Nulliparity
  5. Age at first delivery
  6. Obesity, smoking, alcohol
  7. HRT
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3
Q

Etio of Breast cancer

A

90% sporadic
10% familial

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4
Q

MC gene mutated in Breast cancer

A

P53

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5
Q

Most common gene mutated in familial breast cancer

A

BRCA1

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6
Q

Chromosomes for BRCA

A

BRCA1 - 17q
BRCA 2- 13q

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7
Q

BRCA mutations cause what other cancers

A

Breast
Ovarian
male breast
Pancreatic
Colorectal
Primary peritoneal
Prostate

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8
Q

BRCA 1 type

A

More agg
Poor prognosis
BASAL SUBTYPE
Mc- medullary ca

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9
Q

BRCA 2 type

A

LUMINAL SUBTYPE
better prog

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10
Q

BRCA 2

A

Luminal subtype
Better prog

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11
Q

Risk reduction techniques

A

Bilateral prophylactic mastectomy (95% reduction but ovarian cancer 0% reduction)
B/L salpingo oophorectomy (ovarian 80% and breast 50%)
SERMS- tamoxifen by 47%

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12
Q

Secretory apparatus of breast

A

Acini- lobule- lobe- drained by lactiferous duct—> nipple

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13
Q

Functional unit of breast

A

TDLU

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14
Q

Why upper outer quad Most common?

A

Becz 50% of ductolobular tissue is situated there

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15
Q

Axillary tail of spence enters axilla through

A

Foramen of langer

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16
Q

Involvement of ligament of copper

A

Dimpling

17
Q

Lig of cooper connects

A

Skin to pectoral fascia

18
Q

Polands syndrome

A

Amazia
Absence of sternal portion of pect major
Short webbed fingers

19
Q

Blood supply to breast

A

Internal mammary-60%
Axillary a- 30%

20
Q

Nerves related (during MRM)

A

Long thoracic
Thoracodorsal
Medial and lateral pectoral
Intercostobrachial

21
Q

Levels of ax nodes
(Based on p minor)

A

I- APL
II- central, rotters
III- apical

22
Q

Mammo views

A

CC & MLO

23
Q

Fibrocyastadenosis

A

Now called cyclical mastalgia with nodularity

24
Q

Fibrocystadenosis Features

A

Fluctuant, transilluminant, non tender, cystic with bluish capsule
Called BLUEDOME CYST OF BLOODGOOD

25
Q

Schimmelbusch’s disease

A

When diffuse small, multiple cysts are the main component of fibrocystadenosis.
The MC breast disease

26
Q

Types of Fibrocystadenosis

A

Non prolif
Prolif without atypia
Prolif with atypia

27
Q

Stages Of Fibrocystadenosis

A

Stromal Prolif
Gland prolif
Cyst formation

28
Q

Treatment of Fibrocystadenosis

A

Oil of evening primrose
Gamolenic acid
Danazol
Bromocriptine
Tamoxifen

29
Q

MC non epithelial neoplasm of breast

A

Phyllodes

30
Q

Features of phyllodes swelling

A

Large
Bosselated surface
Smooth, soft, fluctuant
Pressure Necrosis over summit
Skin stretched, red and has dilated veins over it

Surgery (8 decks)

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