Breast Flashcards

1
Q

Benign breast disease

A
fibroadenoma 
breast cysts
mastitis
lactational breast abscess
intraductal papilloma 
radial scar 
fat necrosis 
fibroadenosis
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2
Q

fibroadenoma

A

benign tumours of fibrous and epithelial tissue which arise from lobule.
Highly mobile, encapsulated breast masses that arise from breast lobule storm.

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3
Q

Fibroadenoma management

A

triple assessment: rule out cancer
surgical excision
will regress after menopause if conservatively managed

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4
Q

breast cysts

A

overgrowth of glandular and connective tissue in fibrocystic disease. blocks breast ducts leading to filling of lobules with fluid and distension

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5
Q

mastitis

A

inflammation of breast

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6
Q

mastitis management

A

continue breastfeeding

analgesia

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7
Q

lactational breast abscess

A

infectious mastitis may lead to accumulation of pus in the area of the breast, which can lead to development of abscess.
Most common cause: staph aureus

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8
Q

management of lactational breast abscess

A

early referral to secondary care
incision and drainage or needle aspiration
concomitant ABs

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9
Q

intraductal papilloma

A

benign papillary tumour

Commonly presents as bloody discharge from nipple

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10
Q

radial scar

A

benign sclerosis breast lesion

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11
Q

fat necrosis

A

inflammatory reaction to adipose tissue damage

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12
Q

fibroadenosis

A

inflammation, fibrosis, cyst formation of adenosine of breast.
mote common in upper outer quadrant
Worsens with menstrual cycle

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13
Q

Mammary duct ectasia

A

palpable peri-areolar breast mass caused by inflammation & dilation of Brest ducts
Presents with thick, white nipple discharge

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14
Q

indications for urgent referral to breast assessment clinic

A

Aged >30 with unexplained breast mass

Aged >50 presenting with nipple discharge, retraction or other concerning symptoms

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15
Q

histological subtypes of breast cancer

A

ductal carcinoma
lobular carcinoma
medullary carcinoma
phyllodes tumour

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16
Q

ductal carcinoma of breast

A

most common.
Abnormal proliferation of ductal cells.
Ductal cells lose their acing structure and their nuclei become abnormally large.

17
Q

hormonal receptors of breast cancer

A

oestrogen (ER)
Progesteron (PR)
HER2

18
Q

Management of breast cancers with hormonal receptors

A

ER Positive

  • Premenopausal: Tamoxifen
  • Postmenopausal: Anastrozole

HER2 Positive
- Herceptin

19
Q

Triple assessment of breast cancer

A

clinical exam of breast & surrounding lymph nodes.
Radiological exam
Biopsy

20
Q

Management of breast cancer

A

Surgical management

  • Wide local excision
  • matectomy

Radiotherapy
Chemotherapy

Biological Therapy
- Herceptin (HER2 positive tumour)

hormonal therapy (oestrogen +ve)

  • Premenopausal: Tamoxifen
  • Postmenopausal: Anastrozole
21
Q

cyclical mastalgia

A

breast tendernesss which comes and goes with monthly menstrual cycle

22
Q

malignant phyllodes tumour

A

Rare (1% of breast cancer)

breast cancer of fibroepithelial origin: intraepithelial and interlobular stroll compartments
normally aggressive and fast-growing

typically 40s-50s