bread and butter Flashcards

1
Q

drugs increasing lithium levels

A
[  ] Ace increases
[  ] Loop increases
[  ] Spiro increases
[  ] Ibuprofen increases
[  ] Mtx increases
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2
Q

drugs causing gingival hyperplasia

A

[ ] Ccbs
[ ] Cilosporin
[ ] Phenytoin

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3
Q

antidote to loperamide

A

naloxone

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4
Q

antidote to heparins

A

protamine sulphate

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5
Q

antidote to benzodiazepines

A

flumazenil

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6
Q

antidote to dabigatran

A

idrucizumab

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7
Q

antidote to apix and rivarox

A

andexanet alpha

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8
Q

antidote to digoxin

A

digoxin specific antibody

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9
Q

antidote for methotrexate

A

colonic acid

calcium foliate

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10
Q

QTP?

A
[  ] Amiodarone
[  ] Sotalol
[  ] Macrolides
[  ] Haloperidol
[  ] Ssrus citala and escit
[  ] Tcas
[  ] Antifungals
[  ] Rlccbs
[  ] Atomoxetine
[  ] Methadone
[  ] Domperidone
[  ] Tacrolimus
[  ] All SABA/LABAs
[  ] Quinolones
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11
Q

what juice does warfarin interact with

A

cranberry and pomegranate

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12
Q

what juice does Amiodarone interact with

A

grapefruit

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13
Q

what juice do statins interact with

A

grapefruit

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14
Q

what juice do SSRIs interact with

A

grapefruit

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15
Q

what juice does ciclosporin interact with

A

purple grape,grapefruit and pomelo

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16
Q

what juice does tacrolimus interact with

A

grapefruit,pomelo and pomegranate

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17
Q

CYP450 substrates

A
[  ] Statins
[  ] Amiodarone
[  ] Digoxin
[  ] Montelukast
[  ] Warfarin
[  ] Theophylline
[  ] Benzos
[  ] Ssris
[  ] Tca
[  ] Sildenafil (inhibitors)
[  ] Tamsulosin (inhibitors)
[  ] Sumatriptan
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18
Q

drugs lowering seizure threshold

A
[  ] Theophylline 
[  ] Tramadol
[  ] Quinolones (ibuprofen)
[  ] Lithium
[  ] Antiepileptics
[  ] Orlistat
[  ] Chlorquine
[  ] Mefloquine
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19
Q

drugs causing serotonin syndrome

A
[  ] Tramadal
[  ] Triptans
[  ] Lithium
[  ] Ssris
[  ] Tcas
[  ] Maois
[  ] Bupropion
[  ] Linezolid
[  ] Snris ( venlafaxine)
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20
Q

Drugs causing SJS

A
[  ] Phenytoin
[  ] Carbamazepine
[  ] Lamotrigine
[  ] Galantamine
[  ] Vancomycin
[  ] Co-trimoxazole
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21
Q

hepatotoxic drugs

A
[  ] Itraconazole and antifungals (ketaconazole the most)
[  ] Alcohol
[  ] Amiodarone
[  ] Macrolides
[  ] Benzos
[  ] Carb pheny valproa
[  ] Maoi a phenel and isocarboxazid
[  ] Atomoxetine
[  ] All tb meds except ethambutol
[  ] Flucloxicillin
[  ] Chloramphenicol
[  ] Nitrofurantoin
[  ] Tetracyclines
[  ] Terbinafine
[  ] Mtx
[  ] Sulfasalazine
[  ] Mesalazine
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22
Q

drugs causing pancreatitis

A

[ ] Glutides
[ ] Gliptins
[ ] Valproate
[ ] Carbimazole

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23
Q

drugs causing suicidal ideation

A

[ ] Finasteride
[ ] All antiepileptics
[ ] Atomoxetine
[ ] Varenicicline

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24
Q

drugs causing neuropsychiatric reactions

A

[ ] Mefloquine
[ ] Isotretonoin
[ ] Montelukast
[ ] Quinolones

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25
Q

checking lithium levels after?

A

12 hours

26
Q

check digoxin levels after?

A

6 hours

27
Q

checking gent levels (MDD and ODD)

A

MDD: after 3-4 doses and at dose changes
ODD: 20 hours post dose

28
Q

carbamazepine levels after?

A

1-2 weeks

29
Q

theophylline levels?

A

4-6 hours post dose of mr formulation

5 days after initation and 3 days after any dose changes

30
Q

drugs to avoid tyramine rich foods?

A

MAOIs
isonazid
linezolid

31
Q

drugs causing neuroleptic malignant syndrome?

A

all APs

donepezil

32
Q

with or after food?

A

metronidazole
nitrofurantoin
clarithromycin MR

33
Q

empty stomach

A

[ ] Phenoxymebthylpenicllin
[ ] Tetracycline/oxyteyracyclime
[ ] Flucloxicillin
[ ] Azithromycin- capsules only

34
Q

drugs causing ototoxicity

A
[  ] Clarightromycin and other macrolides
[  ] Cisplatin
[  ] Linezolid
[  ] Vancomycin
[  ] Vinca alkaloids
[  ] Gentamicin
35
Q

drugs causing photosensitivity

A
[  ] Doxycycline
[  ] Isotretenoin
[  ] Tacrolimus
[  ] Amiodarone
[  ] Ciclosporin
[  ] Quinolones
36
Q

drugs causing blood disorders?

A
[  ] Tacrolimus
[  ] Co-trimoxazole
[  ] Sulfasalazine
[  ] Mesalazine 
[  ] antiepileptics
37
Q

tacrolimus interacts with? (an important one)

A

macrolides

38
Q

what colour does nitrofurantoin turn your urine

A

yellow brown

39
Q

rifampicin colour

A

red

40
Q

entacapone colour

A

brown red

41
Q

traimterene colour

A

blue

42
Q

Senna urine colour

A

yellow brown

43
Q

chlorhexidine

A

stains teeth brown

44
Q

POM to P?

A
PPI 
Chloramphenicol 
mometasone 
sildenafil 
maloff 
amrolofine 
sumatriptan
tamsulosin
tranexamic acid 
orlistat
45
Q

drugs causing BMS

A

mycophenalate

all cytotoxic except bleomycin and vincas

46
Q

drugs reducing intestinal mobility

A

[ ] Loperamide
[ ] Codeine
[ ] Metoclopramide

47
Q

drug causing chug Strauss

A

montelukast

48
Q

avoid antacids

A

tetracyclines
quinolone
bisphosphonates

49
Q

drugs causing diarrhoea:

A
colchicine 
antibiotics 
laxatives 
magnesium ant acids 
digoxin 

CALMD

50
Q

Drugs causing constipation

A
al antacids 
AMs
AHs 
AEs
verapamil 
clozapine- refer
51
Q

treating vertigo and tinnitus

A

betahistine

52
Q

pregnancy nausea

A

cyclizine and prochlorperazine

53
Q

treating an acute asthma attack in community

A

pMDI large volume spacer
4pu initially then 2 every 2 minutes for up to 10 puffs
can repeat every 10 minutes- 20 minutes

children: 1 pu every 30-60 seconds up to 10 puffs

54
Q

breath accuated?

A

slow and steady over 4 s

55
Q

DPI breathing

A

quick and deeply

56
Q

pMDI breathing

A

slow and steady

57
Q

potency of:

betametasone valerate

A

potent

58
Q

potency of:

clobetasol propinate

A

very potent

59
Q

potency of clobetasone butyrate

A

moderate

60
Q

potency of hydrocortisone

A

mild

61
Q

potency of nerisone forte?

A

very potent