blood pressure target, cholesterol targets/ intensities

Question 1

Stage 1 hypertension

treat?

Answer 1

140/90- 160/100
lifestyle advice
treat if <80 with organ damage, CVS or 10 year QRISK >10%

Question 2

how should TIA/ IS be treated if normotensive

Answer 2

give antihypertensive even if normotensive

Question 3

stage 2 hTN and treatment?

Answer 3

160/100-180/120

treat all regardless of age

Question 4

stage 3 HTN and treatment?

Answer 4

> 180 SBP or >120 DBP
severe, refer if signs of organ damage: retinal haematoma, papilloedema, confusion etc SAME DAY

if no signs repeat in 7 days

Question 5

<80 years treatment BP target?

Answer 5

<140/90

Question 6

<80 years diabetes, kidney, eye or cerebrovascular disease BP target?

Answer 6

<130/80

Question 7

> 80 years treatment target

Answer 7

<150/90

Question 8

> 80 years diabetes, kidney, eye or cerebrovascular disease BP target?
renal disease target?

Answer 8

renal disease: <140/90

diabetes+ complications: <130/80

Question 9

type 1 diabetic BP target

Answer 9

<135/85 (<130/80 if complications)

Question 10

pregnancy BP target if taking antihypertensives

Answer 10

<135/85

Question 11

what is preeclampsia

prevent with?

Answer 11

BP >140/90 and risk factors e.g. proteinuria presenting after week 20 of pregnancy

Aspirin 75-150mg throughout birth

Question 12

when to offer antihypertensive treatment in pregnancy

Answer 12

sustained BP >140/90

Question 13

when to admit in pregnancy HTN

Answer 13

> 160/110

Question 14

type 2 diabetic HTN target if <80 years

Answer 14

<140/90

Question 15

type 2 diabetic HTN target if >80 years

Answer 15

<150/90

Question 16

target BP in renal disease

if CKD, Proteinuria, diabetes?

Answer 16

140/90 or

<130/80 if CKD, Proteinuria, diabetes

Question 17

less risk of cold extremities BB?

Answer 17

Pindolol
Acebutol
Celiprolol
Oxprenolol

Question 18

BBs which less selectively cross the BBB?

Answer 18

water CANS

Celiprolol
Atenolol
Nadolol
Sotalol

Question 19

Cardioselective BB?

Answer 19

Bisoprolol
Esmolol

Atenolol

Metoprolol
Acebutol
Nebivolol

Question 20

OD BBs?

Answer 20

BACoN 
Bisoprolol 
Atenolol 
Celiprolol 
Nadolol

Question 21

what makes a statin high intensity

examples?

Answer 21

> 40% reduction in LDL

Atorva >20-80
Simva 80
Rousuva 10-40

Question 22

medium intensity statin and examples

Answer 22

30% reduction

atorvastatin 10
fluvastatin 80
rosouva 5

Question 23

highest risk of myopathy with??

Answer 23

ezetimibe with vibrates especially gemfibrozil

Question 24

low intensity statin?

Answer 24

fluva 20-40
prava 10-40
simva 10mg

Question 25

at what level is hypercholesterolaemia diagnosed

Answer 25

> 6mmol/L total

Question 26

TARGETS: total in healthy individuals?

Answer 26

<5mmol/L

Question 27

TARGETS: Total in high risk individuals?

Answer 27

4mmol/L

Question 28

TARGETS: LDL in healthy individuals?

Answer 28

<3mmol/L

Question 29

TARGETS: LDL in high risk individuals?

Answer 29

<2mmol/L

Question 30

TARGETS: HDL target in all?

Answer 30

> 1mmol/L

Question 31

TARGETS: triglyceride levels?

Answer 31

<1.7mmol/L

Question 32

bile acid sequestrant side effects?

Answer 32

stop absorption of ADEK and drugs

take 1 hour before or 4 hours after

Question 33

statin use in pregnancy?

Answer 33

teratogenic

avoid during 3 months prior to conception, during and 1 month after