blood pressure target, cholesterol targets/ intensities Flashcards
Stage 1 hypertension
treat?
140/90- 160/100
lifestyle advice
treat if <80 with organ damage, CVS or 10 year QRISK >10%
how should TIA/ IS be treated if normotensive
give antihypertensive even if normotensive
stage 2 hTN and treatment?
160/100-180/120
treat all regardless of age
stage 3 HTN and treatment?
> 180 SBP or >120 DBP
severe, refer if signs of organ damage: retinal haematoma, papilloedema, confusion etc SAME DAY
if no signs repeat in 7 days
<80 years treatment BP target?
<140/90
<80 years diabetes, kidney, eye or cerebrovascular disease BP target?
<130/80
> 80 years treatment target
<150/90
> 80 years diabetes, kidney, eye or cerebrovascular disease BP target?
renal disease target?
renal disease: <140/90
diabetes+ complications: <130/80
type 1 diabetic BP target
<135/85 (<130/80 if complications)
pregnancy BP target if taking antihypertensives
<135/85
what is preeclampsia
prevent with?
BP >140/90 and risk factors e.g. proteinuria presenting after week 20 of pregnancy
Aspirin 75-150mg throughout birth
when to offer antihypertensive treatment in pregnancy
sustained BP >140/90
when to admit in pregnancy HTN
> 160/110
type 2 diabetic HTN target if <80 years
<140/90
type 2 diabetic HTN target if >80 years
<150/90
target BP in renal disease
if CKD, Proteinuria, diabetes?
140/90 or
<130/80 if CKD, Proteinuria, diabetes
less risk of cold extremities BB?
Pindolol
Acebutol
Celiprolol
Oxprenolol
BBs which less selectively cross the BBB?
water CANS
Celiprolol
Atenolol
Nadolol
Sotalol
Cardioselective BB?
Bisoprolol
Esmolol
Atenolol
Metoprolol
Acebutol
Nebivolol
OD BBs?
BACoN Bisoprolol Atenolol Celiprolol Nadolol
what makes a statin high intensity
examples?
> 40% reduction in LDL
Atorva >20-80
Simva 80
Rousuva 10-40
medium intensity statin and examples
30% reduction
atorvastatin 10
fluvastatin 80
rosouva 5
highest risk of myopathy with??
ezetimibe with vibrates especially gemfibrozil
low intensity statin?
fluva 20-40
prava 10-40
simva 10mg
at what level is hypercholesterolaemia diagnosed
> 6mmol/L total
TARGETS: total in healthy individuals?
<5mmol/L
TARGETS: Total in high risk individuals?
4mmol/L
TARGETS: LDL in healthy individuals?
<3mmol/L
TARGETS: LDL in high risk individuals?
<2mmol/L
TARGETS: HDL target in all?
> 1mmol/L
TARGETS: triglyceride levels?
<1.7mmol/L
bile acid sequestrant side effects?
stop absorption of ADEK and drugs
take 1 hour before or 4 hours after
statin use in pregnancy?
teratogenic
avoid during 3 months prior to conception, during and 1 month after
