Brain Tumours Flashcards

1
Q

most common tumor in adults

A

glioblastoma multiforme

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2
Q

most common benign tumor in adults

A

menigioma

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3
Q

brain tumor associated with NF-2

A

meningioma and schwanomma

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4
Q

brain tumor associated with von hippel lindau

A

hemagioblastoma

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5
Q

malignant adult brain tumour

A

glioblastoma multiforme/ grade IV astrocytoma

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6
Q

adult brain tumors found in frontal lobes

A

glioblastoma multiforme (cerebral hemispheres) and oligodendrocytomas

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7
Q

brain tumor that can cross the corpus callosum

A

glioblastoma multiform/grade IV astrocytoma

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8
Q

GFAP positive brain tumor in adults

A

glioblastoma multiforme

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9
Q

S100+ brain tumor in adults

A

schwannoma

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10
Q

tumor found in convexities of hemispheres and parasagittal regions outside of the brain parenchyma

A

meningioma

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11
Q

cell of origin for meningiomas

A

archanoid cells

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12
Q

new onest of focal seizures

A

meningiomas

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13
Q

dural tail

A

meningiomas

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14
Q

cerebellar tumor in adults

A

hemangioblastoma

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15
Q

cerebellar and retinal tumors in adults suscept

A

von hippel lindaue

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16
Q

can produce polycythemia

A

hemagioblastoma

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17
Q

typically at cerebellopontine angle

A

schwanomma

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18
Q

bilateral schwanommas suspect

A

NF-2

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19
Q

resectbale or treated with sterotatcti radiosurgery

A

schwanommas

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20
Q

positive staingin in schwanomma

A

S100

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21
Q

relatively rare and slow growing adult brain tumor

A

oligodendroglioma

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22
Q

frontal lobe tumor

A

oligodendroglioma

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23
Q

chicken wire capillary patern

A

oligodendroglioma

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24
Q

adult brain tumor that calcifies

A

oligodendroglioma

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25
bitemporal hemianopia
pituitary adenoma
26
sequelae of hyper or hypopituitarism
pituitary adenoma
27
name the tumor: fried egg celsl with round nuclie and clear cytoplasm, calcification and chichen wire capillary pattern
oligodendroglioma
28
name the tumor: along any peripheral nerve
schwanomma
29
name the tumor: closely arranged, thin walled capillaries with minimal intervening parenchyma
hemangioblastoma
30
name the tumor: spindle cells concentrically arranged in a whorled pattern with psammoma bodes/laminated calcifications and firm on gross
menigioma
31
name the tumor: pseudopalisading pleomorphic tumor cells that border central areas of necrosis and hemorrhage
glioblastoma multiforme
32
name the tumor: butterfly
glioblastoma multiforme
33
name the most common brain tumor in children
pilocytic low grade astrocytoma
34
name the most common malignant tumor in childre
medulloblastoma
35
GFAP positive tumor in children
pilocytic low grade astrocytoma
36
where are piloctyic low grade astrocytomas ususally found
in posterior fossa ie cerebellum
37
pilocytic low grade astrocytoma is bening or maligi
bening
38
describe appearance of low grade astrocytoma
well circumsribced with ROESTHAL FIBERS | cystic and solid
39
what is a Rosenthal fibre
eosinophilic corkscrew fibres seen in pilocytic low grade astrocytomas usually in cerbelleum beign in children GFAP positive
40
medulloblastoma benign or maligi
high maligi
41
where is medulloblastoma located
cerebellum
42
histo of medulloblastoma
primitive neuroectoderm tumor ventral in the cerebellum; HOMER WRITGHT ROSETTES small cell sold
43
pathogen of medulloblastoma
compresses 4th ventricle and can lead to noncommunicating hydrocephalus
44
what tumors in children can cause non communicating hydrocephalus
medulloblastoma and ependymoma
45
what tumor can cause drop mets to the spinal cord
medulloblastoma
46
which tumor in hcildre is hemorrhagic
medulloblastoma
47
I say homer wright you think
medulloblastoma
48
I say solid tumor you think
medulloblastoma
49
location fo ependymoma
most commonly in the 4th ventrcile
50
prognosis of ependymoma
poor
51
describe histopathos of ependymoma
perivascular roesstes with rod shaped blepharoplasts/basal siliary bodies found near nucleus
52
what is a bracniopahryngioma
bening childhood tumor derives from remants of trahtke pouch
53
what is the most common childhood upratentorial tumor
craniopharygioma
54
what two tumors present similarly with unquie visual changes
bitemporal hemanopia in craniopharygioma and pituitary ademona
55
what three tumors calcify
meningioma oligodendroglioma craniopharyngioma
56
histopathos of craniopahrymgioma pelase
tooth enale like calcifications
57
what causes herniations
increase ICP and portion of brain can become displaced
58
what herniation can compress the ACA
subfalcine hernation: cingulate gyrous moves under the falx cerberi
59
``` presentation: left EOM problems left dilation of pupil left motor weakness left occipital lobe infarct at pca ```
uncal herniation
60
what happens in an uncal hernation
medial temporal lobe moves down into the tetorium cerebelli
61
why do motor signs show up on same side as occipital symptoms in an uncal hernation
compresses contralateral crus -- KERNOHAN NOTCH cuses a fals localization sign
62
what dose compression of the PCA cause
ipsilateral PCA causes contralateral homonymous hemianopia - same side of brain affected
63
what is kernohans notch
contralateral crus cecrebri - causes motor weakness on ipsilateral side
64
what is consequents of downward transtenroial/central hreniation
caudal displacement of brain stem cau;ses DURET HEMORRHAGES - paramedian branches of the basilar artery - usually fatal
65
duret hemorrhages associated with?
downward transtentorial/cenral herniation
66
which two types of herniations are fatal
downward transtentoria;/central hernation (rips paramedian branches of basilar artery ) cerebellar tonsillar hernation into foramen mangeum - cardiorespiratory arrest
67
what hernation causes cerebellar coning
cereberlal tonsillar herniation
68
what hernation compresse the brain stem resulting in coma and death
cerebellar tonsil herniation into the foremane magnum.
69
what passes through the foreamne magnum
spina roots of CN XI brain stem vertebral arteries