Brain Regions/Functions – Hindbrain, Midbrain, and Subcortical Forebrain Structures Flashcards
Hindbrain Structures
Medulla Oblongata
Pons
Cerebellum
Medulla
Located above the spinal cord.
Controls involuntary actions like swallowing, coughing, and sneezing.
Regulates essential functions such as respiration, heart rate, and blood pressure.
Vulnerable to disruption from brain injury, diseases, and certain drugs like opioids.
Pons
Connects the two halves of the cerebellum.
Coordinates movements on both sides of the body.
Relays messages between the cerebellum and cerebral cortex.
Plays a role in respiration and sleep regulation.
Cerebellum
Coordinates voluntary movements and maintains posture and balance.
Damage can cause ataxia, impairing muscle control and coordination.
Involved in processing and storing procedural memories.
Contributes to non-motor functions like attention, language processing, and visuospatial abilities.
Midbrain Structures
Reticular Formation
Substantia Nigra
Reticular Formation
Network of neurons extending from the medulla to the midbrain.
Regulates muscle tone, eye movements, and pain.
Contains the reticular activating system (RAS) responsible for consciousness, arousal, and sleep-wake cycles.
Lesions can lead to coma, while stimulation can awaken a sleeping person.
Substantia Nigra
Involved in reward-seeking behavior and motor control.
Degeneration of dopamine-producing cells leads to symptoms of Parkinson’s disease.
Subcortical Forebrain Structures:
Hypothalamus
Thalamus
Basal Ganglia
Limbic System (includes amygdala, cingulate cortex, hippocampus)
Hypothalamus
Maintains body homeostasis, regulating temperature, blood pressure, hunger, and sleep.
Influences sexual and reproductive behaviors.
Involved in aggression and emotional reactions.
Contains the suprachiasmatic nucleus (SCN) regulating circadian rhythms.
Thalamus
Acts as a relay station for sensory information (excluding smell) to the cortex.
Coordinates sensory and motor functions and plays a role in memory.
Damage can lead to Korsakoff syndrome, characterized by amnesia and confabulation.
Basal Ganglia
Comprises the striatum (caudate nucleus, putamen, nucleus accumbens) and globus pallidus.
Initiates and controls voluntary movements, procedural learning, and cognitive functions.
Associated with mood disorders, ADHD, OCD, and Parkinson’s disease.
Limbic System
Includes the amygdala, cingulate cortex, and hippocampus.
Amygdala regulates emotions, fear responses, and memory formation.
Cingulate cortex influences motivation, memory, and emotional reactions to pain.
Hippocampus plays a crucial role in memory consolidation and spatial memory.
Korsakoff Syndrome:
Location: Thalamus and Mammillary Bodies
Description: Neurological disorder resulting from thiamine deficiency, often due to chronic alcoholism. Characterized by severe anterograde amnesia, retrograde amnesia, and confabulation.
Parkinson’s Disease:
Location: Substantia Nigra
Description: Neurodegenerative disorder caused by the degeneration of dopamine-producing cells in the substantia nigra. Symptoms include slowed movement, tremors, rigidity, and other motor symptoms.
Alzheimer’s Disease:
Location: Hippocampus and Entorhinal Cortex
Description: Progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes. Degeneration of cells in the hippocampus and entorhinal cortex leads to impairments in episodic memory and spatial navigation.