Brain Imaging And Techniques Flashcards

1
Q

Nissl Stains

A
  • stains the nucleus of a neuron

* cell bodies

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2
Q

Myelin Stains

A

Pathways

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3
Q

Immunocytochemistry

A
  • based on the binding of labeled protein-specific antibodies
  • Immune response- antibodies created that bind and remove/destroy antigens
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4
Q

In Situ hybridization

A

Uses labeled DNA to locate neurons with complementary mRNA

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5
Q

Stereotactic Atlas

A

Shows the location of key structures on images of a series of brain sections.

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6
Q

Stereotactic Imstrument

A

Places an electrode or other device at a precise location in the brain

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7
Q

Lesions and Ablations

A

Removal or damage of a specific brain area

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8
Q

Stimulation

A

Electrically stimulate a specific brain Area

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9
Q

Injections

A

Inject chemicals through an implanted cannula

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10
Q

Microdialysis

A

Extract CSF and analyze chemicals

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11
Q

Structural

A

CT or CAT: Computer assisted tomography

MRI: magnetic resonance imaging

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12
Q

Functional Neuroimaging

A

PET: positron emission tomography

fMRI: functional magnetic resonance imaging

EEG: electroencephalograph

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13
Q

CT or CAT Scans

A
  • Dye injected into the blood
  • Series of x-rays is made from different angles that reflect the density of blood vessels in each area
  • Detects bedding, brain damage and skull fractures, brain tumors
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14
Q

MRI

A
  • Measure the radio-frequency waves emitted by the hydrogen atoms when they are subjected to an strong magnetic field
  • Detailed view of the brain; 3D
  • Reasonably fast, inexpensive, and even portable
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15
Q

PET

A
  • Injects radioactive substance (glucose) into bloodstream
  • Scanners captures positrons emitted by the radioactive substance and is color coded to show relative amounts of activity
  • Used to monitor blood flow or oxygen uptake to detect receptors for specific neurotransmitter
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16
Q

fMRI

A
  • Provides images of brain structure and activity
  • Used strong magnetic field
  • Structure is imaged using waves emitted from brain by hydrogen ions
  • Imaged using signal created from interaction b/t oxygen and iron in the blood
17
Q

EEG

A
  • Measures gross electrical activity of the brain, the combined activity from many neurons
  • Uses electrodes attached to the scalp
  • Good temporal resolution but poor spatial resolution due to distortion through skull
  • Best used to detect changes in arousal, epilepsy, sleep research