Brain Imaging And Techniques Flashcards
Nissl Stains
- stains the nucleus of a neuron
* cell bodies
Myelin Stains
Pathways
Immunocytochemistry
- based on the binding of labeled protein-specific antibodies
- Immune response- antibodies created that bind and remove/destroy antigens
In Situ hybridization
Uses labeled DNA to locate neurons with complementary mRNA
Stereotactic Atlas
Shows the location of key structures on images of a series of brain sections.
Stereotactic Imstrument
Places an electrode or other device at a precise location in the brain
Lesions and Ablations
Removal or damage of a specific brain area
Stimulation
Electrically stimulate a specific brain Area
Injections
Inject chemicals through an implanted cannula
Microdialysis
Extract CSF and analyze chemicals
Structural
CT or CAT: Computer assisted tomography
MRI: magnetic resonance imaging
Functional Neuroimaging
PET: positron emission tomography
fMRI: functional magnetic resonance imaging
EEG: electroencephalograph
CT or CAT Scans
- Dye injected into the blood
- Series of x-rays is made from different angles that reflect the density of blood vessels in each area
- Detects bedding, brain damage and skull fractures, brain tumors
MRI
- Measure the radio-frequency waves emitted by the hydrogen atoms when they are subjected to an strong magnetic field
- Detailed view of the brain; 3D
- Reasonably fast, inexpensive, and even portable
PET
- Injects radioactive substance (glucose) into bloodstream
- Scanners captures positrons emitted by the radioactive substance and is color coded to show relative amounts of activity
- Used to monitor blood flow or oxygen uptake to detect receptors for specific neurotransmitter