Brain Development And Plasticity

Question 1

Neurulation

Answer 1

Neural tube forms

Question 2

Anencephaly

Answer 2

Rostral neural tube doesn’t close

Question 3

Spinal bifida

Answer 3

Causal neural tube doesn’t close

Question 4

Proliferation- Ventricular Zone

Answer 4

• Cell moves toward Pial surface
• Cells DNA is copies
• Cell comes back to ventricular surface
• Cell retract arms
• Cell divides in two

Question 5

Growth and Development of neurons

Answer 5

• Proliferation- ventricular zone
• Migration- radial glia
• Differentiation- appearance of neuronal features
• Circuit formation- atonal path finding

Question 6

Circuit Pruning

Answer 6

• “weak synapses” are eliminated

* leads to apoptosis- programmed cell death

Question 7

Neuroplasticity

Answer 7

• Dendritic branching- more surface area
• Compensation- uninjured tissue can take over the function of lost neurons
• Cortical Reorganization- functions of damaged areas are assumed by nearby areas-rewiring
• Neurogenesis- birth of new neurons