BPH Drugs: Alpha 1 blockers

Question 1

Tamsulosin & Terazosin-MoA

Answer 1

1. both are alpha 1 adrenergic blockers
2. prevent continuous smooth muscle contraction within the prostate tissue –> decrease in overall prostatic pressure so that bladder pressure>prostate pressure –> urine release

Question 2

Tamsulosin & Terazosin-Side Effects

Answer 2

1. orthostatic hypotension