BPD

Question 1

Acute Setting of BPD

Answer 1

Lithium and an SGA (such as aripiprazole, olanzapine, risperidone, or ziprasidone)

Question 2

Maintenance Therapies BPD

Answer 2

Quetiapine, aripiprazole, and ziprasidone

Question 3

Lamotrigine

Answer 3

Anti-eleptic
BPD 1 maintenance. Not appropriate for acute mania
Side effects: Most likely of SGAs for SJS

Question 4

Quetiapine

Answer 4

SGA
Side effects: Increased BG and QT prolongation.
Sedation, weight gain, diabetes
Least likely for movement disorders

Question 5

Valproate

Answer 5

For severe mania in combination with an SGA, as an alternative to Lithium with an SGA
BB: Hepatotoxicity and pancreatitis

Question 6

Lithium

Answer 6

Mood stabilizer.
First line in BPD.
Toxicity: Renal dysfunction, prolonged QTc, weakness, muscle twitching, confusion
Does NOT affect liver

Question 7

Antisocial

Answer 7

Therapy but also an SGA (Risperidone or Quetiapine)

Question 8

Risperidone

Answer 8

SGA
Most likely for elevated serum prolactin levels (=nipple discharge)
Side effects: weight gain, glucose abnormalities, and orthostatic hypotension

Question 9

Aripiprazole

Answer 9

Low chance QTc prolongation, or weight gain.
Watch for irritability.