Bordetella Pertussis Flashcards

1
Q

BORDETELLA PERTUSSIS

A

3 stages / 7-17 days symptom onset / 6-week symptom duration

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2
Q

A 16-month-old infant presents to clinic with c/o sneezing, decreased appetite, and hacking cough that began at night but is now
occurring during the day. What is high on your diagnosis differential of this patient?
A: RSV
B: Legionnaires disease
C: Pertussis
D: Epiglottitis

A

C: Pertussis

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3
Q

What is the typical incubation period for pertussis?

A

Answer: 7-17 days

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4
Q

T or F: infants are reservoirs of pertussis whereas adults / adolescents are most affected

A

Answer: False, infants are most affected whereas adults/adolescents are reservoirs

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5
Q

How is pertussis transmitted between humans?

A

Answer: droplet transmission

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6
Q

Approximately how long do symptoms last and what is unique about symptom progression?

A

Answer: last about 6 weeks, occur in 3 consecutive stages; cough that is intermittent and turns paroxysmal

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7
Q

Stage 1 of pertussis is called what?

A

Answer: Catarrhal

Copious discharge of mucus associated with inflammation of mucous membranes, especially of the nose and throat.

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8
Q

Stage 2 of pertussis is called what?

A

Answer: Paroxysmal

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9
Q

Stage 3 of pertussis is called what?

A

Answer: Convalescent

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10
Q

What is the typical symptom presentation in stage 1 (Catarrhal)?

A

Answer: insidious onset of lacrimation, sneezing, coryza, anorexia, malaise, hacking night cough that becomes day cough

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11
Q

What is the typical symptom presentation in stage 2 (Paroxysmal)?

A

Answer: bursts of rapid, consecutive coughs followed by deep, high-pitched inspiration (inspiratory whoop)

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12
Q

What is the typical symptom presentation in stage 3 (Convalescent)?

A

Answer: begins 4 weeks after onset with decrease in frequency / severity of paroxysms of cough

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13
Q

In adult patients, what must be part of your differential when a cough has been present for more than 2 weeks?

A

Answer: pertussis

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14
Q

What is the typical lab / diagnostic findings suggestive of pertussis?
A: PO2 <90%
B: WBC >15,000-20,000
C: Patchy opacities and lobar consolidation (CXR)
D: gram + bacteria (blood cultures)

A

B: WBC >15,000-20,000

Answer: B (patchy opacities/lobar consolidation is pneumonia; pertussis is a gram-negative bacteria)

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15
Q

The FNP knows the gold standard to diagnosing a patient pertussis is?

A

Answer: nasopharyngeal culture (Bordet-Gengou agar)

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16
Q

What is the best prevention for pertussis

A

Answer: DTaP vaccine (11-18 yr. old whose received DTP/DTaP should receive a SINGLE dose of either Tdap product; >64 yr needs a single dose of Tdap; during EACH PREGNANCY, receive a single dose of Tdap regardless of previous vaccine hx)

17
Q

What is the appropriate treatment for pertussis?

A

Answer: antibiotics – MYCINS (erythromycin, azithromycin, clarithromycin, or Bactrim)