Bones

Question 1

Vertebrae and ribs are?

Answer 1

Trabecular

Question 2

Which type of bone has a more metabolic function?

Answer 2

Trabecular (aka cancellous)

Question 3

Lamellar bone is?

Answer 3

Mature bone

Collagen fibres in alternating orientations

Question 4

What makes bone woven?

Answer 4

Immature

Disorganised collagen fibres

Seen in states of high bone turnover eg healing, tumours and pagets

Question 5

Osteoclasts activated by?

Answer 5

RANK-RANKL interaction

Question 6

ALP produced by?

Answer 6

Osteoblasts

Question 7

Cause of osteomyelitis in adults?

Answer 7

Staph A

Question 8

Osteomyelitis in neonate?

Answer 8

Haemophilus influenza and GBS

Question 9

Treatment for rheumatoid A?

Answer 9

Methotrexate

Question 10

Histo for rheumatoid A?

Answer 10

Proliferative synovitis

Question 11

Chinese letters on histology with soap bubble osteolysis and shepherds crook deformity?

Answer 11

Fibrous dysplasia

Question 12

McCune Albright syndrome?

Answer 12

Poly-ostotic fibrous dysplasia (mono-ostotic more common in fibrous dysplasia alone)

+ cafe au lait spots

+ precocious puberty

Question 13

Speckled mineralisation

Answer 13

Osteoblastoma

Question 14

Most common skeletal neoplasm?

Answer 14

Osteochondroma

Question 15

Affects the HANDS in 43% with popcorn/cotton wool like calcification and O ring sign

Answer 15

Enchondroma

Question 16

Radiolucent nidus with sclerotic rim?

Answer 16

Osteoid osteoma

Question 17

Affects head and neck and seen in gardeners syndrome (similar to FAP)

Answer 17

Osteoma

Question 18

Codman’s triangle with sunburst appearance

Answer 18

Osteosarcoma

Question 19

Fluffy calcification in the AXIAL skeleton

Answer 19

Chondrosarcoma

Question 20

CD99
t(11;22) translocation
Onion skinning of periosteum

Answer 20

Ewing’s sarcoma

Question 21

Long bones are generally?

Answer 21

Cortical