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Histology 2ndYR 1stSem Midterms > Bone Tissue > Flashcards

Bone Tissue Flashcards

1
Q

Other functions of Bone Tissue aside from protecting organs

A

Hematopoiesis & Reservoir for Calcium and minerals

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2
Q

A.k.a Blood cell formation

A

Hematopoiesis

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3
Q

Cells derived from Osteoprogenitor Cells

A

Osteoblasts

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4
Q

Function of Osteoblasts

A

Synthesize, secrete, & deposit Osteoid

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5
Q

How are osteoblasts arranged, and where?

A

Arranged as a layer of cuboidal/columnar cells on the bone surface

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6
Q

Osteoblasts mature into?

A

Osteocytes

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7
Q

Osteocytes are found/located where?

A

Lacunae

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8
Q

What do osteocytes use for communication and exchange of metabolic products and nutrients

A

Canaliculi

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9
Q

Functions of osteocytes

A

Maintain homeostasis of bone, and blood concentrations of calcium & phosphate

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10
Q

Multinucleated cells of the bone tissue

A

Osteoclasts

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11
Q

Osteoclasts occupy shallow concavities called what?

A

Howship’s Lacunae

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12
Q

Function of Osteoclasts

A

Resorption, Remodeling, & Bone Repair

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13
Q

Two components of Bone Matrix

A

Inorganic & Organic

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14
Q

Component of Bone Matrix that resists compression

A

Inorganic

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15
Q

Component of Bone Matrix that resists tension

A

Organic

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16
Q

Two layers of a Periosteum

A

Outer Fibrous & Inner Cellular

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17
Q

Bundles of Periosteal collagen that penetrate the bone matrix and bind the periosteum to the bone (found in the Outer Fibrous layer)

A

Perforating Fibers / Sharpey Fibers

18
Q

Cells found in the Inner cellular layer of the periosteum

A

Osteoblasts & Osteoprogenitor cells

19
Q

Covers small trabiculae of bony matrix that project into marrow cavities

A

Endosteum

20
Q

Types of Bone Tissues

A

1.) Lamellar, Mature, Secondary Bone
2.) Woven, Immature, Primary Bone

21
Q

Which bone tissue is stronger? Primary or Secondary?

A

Secondary (mature) is stronger than Primary (immature)

22
Q

Types of Secondary (Mature) Bone

A

1.) Compact
2.) Cancellous/Spongy

23
Q

Compact bone is __% of total bone mass

A

80%

24
Q

Structural units of Compact bone

A

Osteons

25
Q

Osteons are surrounded by?

A

Interstitial Lamellae

26
Q

Spongy bone is __% of total bone mass

A

20%

27
Q

Spaces between the trabeculae are filled with?

A

Red bone marrow

28
Q

Arrangement of collagen fibers in Primary (Immature) Bone

A

Random Orientation of collagen fibers

29
Q

Type of bone tissue seen during fetal bone development and bone repair

A

Woven, Immature, Primary bone tissue

30
Q

Two type of Ossification in Osteogenesis

A

1.) Intramembranous Ossification
2.) Endochondral Ossification

31
Q

Type of Ossification where osteoblasts differentiate directly from mesenchyme and begin secreting osteoid

A

Intramembranous Ossification

32
Q

Type of Ossification that forms most bones of the body

A

Endochondral Ossification

33
Q

Type of Ossification where bone develops directly from sheets of mesenchymal connective tissue

A

Intramembranous Ossification

34
Q

Type of Ossification where bone develops by replacing the preexisting hyaline cartilage

A

Endochondral Ossification

35
Q

5 Stages of Endochondral Ossification

A

1.) Zone of Reserve Cartilage
2.) Proliferative Zone
3.) Zone of Hypertrophy
4.) Zone of Calcified Cartilage
5.) Zone of Ossification

36
Q

Identify what stage (zone) of Endochondral Ossification

  • resting cartilage
  • shows chondrocytes in their lacunae
A

Zone of Reserve Cartilage

37
Q

Identify what stage (zone) of Endochondral Ossification

  • cartilage cells divide repeatedly,
  • enlarge & secretes more type II collagen & proteoglycans
  • chondrocytes are organized into columns parallel to the long axis of the bone
A

Proliferative Zone

38
Q

Identify what stage (zone) of Endochondral Ossification

  • Chondrocytes in lacunae increase in size as a result of swelling of the nucleus & cytoplasm
A

Zone of Hypertrophy

39
Q

Identify what stage (zone) of Endochondral Ossification

  • chondrocytes undergo apoptosis
  • releases matrix vesicles & osteocalcin
  • begins matrix calcification by formation of hydroxyapatite crystals
A

Zone of Calcified Cartilage

40
Q

Identify what stage (zone) of Endochondral Ossification

  • bone tissue first appears
  • osteoblasts settle in a later of the spicules of calcified cartilage matrix
  • secrete osteoid which becomes the woven, immature, primary bone
A

Zone of Ossification

Histology 2ndYR 1stSem Midterms (5 decks)

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