bone structure, classification, metabolism and devlopment Flashcards

1
Q

smawhat is a bone

A

‘ A bone is a mineralised connective tissue that exabits four types of cells,: Osteoblasts, bone lining cells, osteocytes and osteoclasts

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2
Q

why do we need bones?

A
  • Provide shape and support for the body
  • Protection for certain organs such as the lungs
  • Environment for marrow
  • Storage area for minerals
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3
Q

bone composition?

A
  • The weight of bones can vary significantly depending on individual factors
  • Age, sex, body composition play a role in determining this
  • Bones on average make up around 15% of an individual’s total weight
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4
Q

why is understanding bone pathology important to overall health?

A
  • Research
  • Developing treatments
  • Managing chronic conditions
  • Provides greater understanding of genetic determinants of health
  • Visualise conditions radiographically
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5
Q

bones are composed of cells, what are the main three cateogories?

A
  • osteoblasts
  • osteocytes
  • osteoclasts
    Cells have different roles of functions and work together to facilitate bone formation, strength and remodelling
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6
Q

what is an osteoclast?

A

osteoclast is a type of bone cell that breaks down the bone tissue

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7
Q

what is an osteoblast?

A

osteoblasts are cells that synthesise bone

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8
Q

what are osteocytes?

A

osteocytes are osteoblasts trapped in the matrix that they secrete

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9
Q

osteoblasts function activity and location?

A

function = Bone forming cells and Secretes organic components such as collogen
activity = Bone formation during growth, repair and remodelling
location = bone surface

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10
Q

osteocytes function, activity and location?

A

function = Mature cells from osteoblasts
Maintain bone tissue
Regulate mineral homeostasis
activity = Form a communication network through canaliculi, allowing nutrient exchange and waste products
location = lacunae

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11
Q

osteoclasts function, activity and location?

A

function = Large cells responsible for bone resorption, break down and removes old or damaged tissue
activity = Release enzymes and acids, which facilitates the remodelling
location = site of bone resorption, often the bone surface

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12
Q

what is an axial skeleton?

A

Provides support and protection for vital organs including the brain, spinal cord, heart and Lungs.

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13
Q

what is an appendicular skeleton?

A

Facilitates movement and interaction with the external environment, integral to walking, running and using our hands

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14
Q

what type of bones are there?

A

Long bones
Short bones
Flat bones
Irregular bones
Sesamoid bones
Sutural bones

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15
Q

long bone?

A

explanation = Long and slender, the femur is a long bone and the largest and heaviest bone in the body
example = humerus

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16
Q

flat bone?

A

explanation = Thin, parallel surfaces, provide protection and due to surface areas serve as good attachment sites
example = scapula

17
Q

sesamoid bone?

A

explanation = Usually small, round and flat. Sesamoid bones are within this, but not everyone has them
example = patella

18
Q

irregular bone?

A

explanation = Complex shape with several characteristics, can have flat, round, short, notched or rigid surfaces
example = Vertebrae

19
Q

short bone?

A

explanation = Usually small in appearance and for that reason are usually rigid and difficult to damage
example = carpal bones

20
Q

sutural bone?

A

explanation = Exclusive to the skull and are small and flat with a unique shape and mimic the shape of a jigsaw puzzle
example = regions of the skull

21
Q

bone metabolism?

A

osteoblasts and osteoclasts play a pivotal role in bone remodelling

22
Q

bone density?

A
  • Reduced bone density is commonly associated with conditions such as osteopenia and osteoporosis.
  • Bones with low bone density are weakened and more susceptible to fractures and injury.
  • Individuals with low bone density has several key metabolic changes compared to healthy bone
23
Q

altered hormone regulation?

A

Hormonal levels of estrogen and testosterone reducing can accelerate bone loss