Bone Sarcoma

Question 1

Ewing’s sarcoma
-population often affected
-bones affected
-presentation
-investigation findings
-management

Answer 1

Children and YP
Pelvis, long bones => severe pain, swelling
May cause limited ROM, easy fractures

Onion skin appearance on Xray - periosteal reaction
Bone biopsy
BM sample
PETCT

Surgery
Chemo, RT

Question 2

Osteosarcoma
-population often affected
-bones affected
-risk factors
-presentation
-investigation findings
-management

Answer 2

MOST COMMON PRIMARY BONE TUMOUR
Children and YP -
Metaphysis of long bones before fusion of growth plates

Rb gene - increased risk of osteosarcoma + retinoblastoma
Pagets
RT

Swollen
Painful when touched
May cause limited ROM, easy fractures

Codman traingle on Xray
Sunburst pattern

Bone biopsy
PETCT

Surgery
Chemo, RT

Question 3

Chondrosarcoma
-population often affected
-bones affected
-presentation
-investigation findings
-management

Answer 3

Cancer of the cartilage

40+ in men
Humerus, femur, pelvis, ribs, spine

Swollen, painful when touched
May cause limited ROM, easy fractures

Bone biopsy
MRI
CT
PETCT

Surgery
Chemo, RT

Question 4

2ww criteria for bone sarcoma

Answer 4

V URGENT (U48HRS) for assessment of children and young people with Xray suggestive of bone sarcoma