Bone Marrow Failure Flashcards
1
Q
Aplastic anemia
A
Decreased BM cellularity and cell production
Inherited or acquired via T cell
Damage to BM, replaced with fat
Treat with transfusion, SCT, immunosuppression
2
Q
Pure red cell aplasia
A
Anemia, reticulocytopenia, T cell depletion
3
Q
MDS
A
Infective hemaptopoiesis, risk of AML
Nonspecific symptoms
CD34+ cells, giant platelets, hyper cellular
4
Q
Myelophthysis
A
2ary myelofibrosis
Caused by malignant, TB, previous radiation
Increased fibroblasts