Bone Marrow Failure Flashcards

1
Q

Aplastic anemia

A

Decreased BM cellularity and cell production

Inherited or acquired via T cell

Damage to BM, replaced with fat

Treat with transfusion, SCT, immunosuppression

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2
Q

Pure red cell aplasia

A

Anemia, reticulocytopenia, T cell depletion

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3
Q

MDS

A

Infective hemaptopoiesis, risk of AML

Nonspecific symptoms

CD34+ cells, giant platelets, hyper cellular

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4
Q

Myelophthysis

A

2ary myelofibrosis

Caused by malignant, TB, previous radiation

Increased fibroblasts

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