Bone Marrow

Question 1

colony forming unit (CFU)

Answer 1

a single cell, residing in the bone marrow, capable of differentiating into colonies of specific hematopoeitic cells; all CFUs, regardless of the cell type produced, are phonologically indistinct, most closely resembling small lymphocytes

Question 2

erythropoietin

Answer 2

a glycoprotein hormone produced mainly by endothelial cells of the peritubular capillary plexus in the kidney that stimulates erythropoesis; chronic kidney disease often results in anemia due to decreased erythropoietin production

Question 3

hemopoiesis (hemtopoiesis)

Answer 3

the formation and development of blood cells; occurs primarily in the bone marrow after birth

Question 4

erythropoiesis

Answer 4

the formation and development of erythrocytes

Question 5

leukopoiesis

Answer 5

the formation and development of leukocytes

Question 6

granulopoiesis

Answer 6

the formation and development of granulocytes

Question 7

lymhocytopoiesis

Answer 7

the formation and development of lymphocytes

Question 8

monocytopoiesis

Answer 8

the formation and development of monocytes

Question 9

thrombocytopoiesis

Answer 9

the formation and development of platelets (thrombocytes)

Question 10

left shift

Answer 10

an increased concentration of band nuetrophils in the blood; indicative of a condition stimulating nuetrophil consumption/production

Question 11

myeloid

Answer 11

pertaining to, derived from, or manifesting certain features of the bone marrow; often used to refer collectively to leukocyte precursors in the bone marrow

Question 12

myeloid-erythroid (M:E) ratio

Answer 12

the ratio of leukocytic to erythrocytic precursor cells in the bone marrow; normally varies from 1:1 to 4:1; mature erythrocytes are not included in “erythroid” count of bone marrow cells

Question 13

right shift

Answer 13

an increased concentration of mature neutrophils, usually with an increased number of nuclear lobes (=hypersegmented), in the blood