Bone disorders Flashcards
what mode of inheritance is seen in osteopetrosis
autosomal recessive
who is osteopetrosis most common in
young children
what do you get in osteopetrosis
dense and brittle bones
what would you see on radiology of a patient with osteopetrosis
lack of differentiation between cortex/medulla
how does osteopetrosis present
signs of anaemia and thrombocytopenia
what is osteogenesis imperfecta
defective osteoid formation due to a congenital inability to produce adequate intracellular substances (eg. osteoid, collagen)
what would you see on radiology of osteogenesis imperfecta
multiple fractures
wormian bones
trefoil pelvis
what causes rickets
vitamin D deficiency
what happens in rickets
failure of the osteoid to ossify
what might you see in rickets
bowing of femur and tibia
large head
deformity of chest wall w/ thickening of costrochondral junction
