Bone Density Flashcards

1
Q

indications for BMD

A
  • primary and secondary osteoporosis or osteopenia
  • monitoring treatment (HRT, calcitonin, etc.)
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2
Q

what is secondary osteoporosis/osteopenia?

A

result of other systemic disorders or medications/treatments that causes an imbalance in bone remodelling

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3
Q

primary osteoporosis

A

associated with the aging process; divided into Type I and Type II

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4
Q

Type I osteoporosis

A

in post-menopausal women due to the decreased estrogen levels

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5
Q

Type II osteoporosis

A

in men and women
- due to the general decrease ability to build new bone as we age

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6
Q

what role does hyperparathyroidism have on bone formation?

A

it causes increase in PTH = increase bone resorption = which increases serum Ca

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7
Q

post-menopausal women and men 50-64
what makes then at risk?

A

fragility #, parental hip #, vertebral # or osteopenia on x-ray, smoker, high alcohol intake, those with a lower body weight, RA, and major weight loss (>10% of body weight at age 20)

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8
Q

women and men younger than 50
what makes them at risk?

A

fragility #, premature menopause (before age 45), malabsorption syndrome, primary hyperparathyroidism, secondary osteoporosis, prolonged use of glucocorticoids, hypogonadism

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9
Q

what are the contraindications for BMD?

A
  • recent barium study (1 week is okay)
  • CT or MR with contrast (1 week)
  • NM study within 10 t1/2
  • spine, hip or radius #, hardware or grafts at the specific sites
  • pregnancy
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10
Q

how do you correctly identify the lumbar vertebrae?

A

count vertebrae starting from bottom up
L5 immediately above sacrum

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11
Q

what are the characteristics of the L1-L4 an L5?

A

L1-L3 = u shape
L4 = H shape
L5 = dog bone on its side

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12
Q

t-score

A

Comparison between patients to reference population with peak bone density
*still sex matched but not aged matched
SD from 25-30 yo

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13
Q

Z score

A

Patients are compared to an age-and-sex-matched database
SD from normal

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14
Q

What is the absolute value of the results?

A

Greater than 1g/cm2 is normal

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15
Q

WHO BMD relative values are for which group of people?

A

Women and men over 50

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16
Q

Normal t score

A

No more than 1 SD below mean
(> -1)

17
Q

Osteopenia t score

A

-1 to -2.5 SD from mean

18
Q

Osteoporosis t score

A

> -2.5 SD from mean

19
Q

How are patients placed into their respective t score?

A

Based on the category of their lowest t score value from all the sites measured

20
Q

Women and men under 50 are compared to what score?

A

Z scores

21
Q

What is considered normal for men and women under 50 then?

A

> -2.0 SD

22
Q

What are independent risk factors?

A

Sex and age

23
Q

Fragility #

A

Fall from standing height

24
Q

LSC

A

Least significant change
- measured so we can ensure that the difference is due to the patients changes and not the machine