Bone

Question 1

Mesenchymal stem cells that develops into osteoblasts

Answer 1

Osteogenic Cells

Question 2

Cell that forms bone matrix (osteoid- organic ECM), signal for bone calcification

Answer 2

Osteoblast

Question 3

Cell that maintains bone tissue (completely surrounded by bone matrix); resides in lacunae

Answer 3

Osteocyte

Question 4

Mobile cell that functions in resorption (breakdown) of bone matrix

Answer 4

Osteoclast

Question 5

The bone ECM consists of:

Answer 5

• Osteoid (organic)- type 1 collagen and bone matrix proteins (BMPs- GAGs, glycoproteins, osteocalsin, osteonectin)
• Inorganic- hydroxyapatite crystals

Question 6

Osteoclasts breakdown bone matrix with acidic environment near the _____ at the _____

Answer 6

Ruffled border

Resorption bay (Howship Lacunae)

Question 7

Osteon development occurs by ____ excavating tunnel through old bone and ____ filling the tunnel with new bone

Answer 7

Osteoclasts

Osteoblasts

Question 8

____ Canals connect the Central (_____) Canal to blood vessels

Answer 8

Volkmann’s

Haversian

Question 9

Older, broken down osteoid become _____

Answer 9

Interstitial lamella