body fluids Flashcards

1
Q

total body fluid

A

42 L

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2
Q

extracellular fluid - plamsa

A

3L

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3
Q

extracellular fluid - interstitial fluid

A

10L

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4
Q

extracellular fluid - transcellular fluid

A

1L

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5
Q

intracellular fluid

A

28 L

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6
Q

rough water intake daily

A

2 L

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7
Q

daily urine production

A

800 - 2000 ml/day

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8
Q

volume of other water loss

A

skin = 300-400ml

respiratory tract = 300-400 ml

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9
Q

ext Na+

A

140 mM

135-145

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10
Q

ext K+

A

4 mM

3.5-5

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11
Q

ext Ca2+

A
  1. 4 mM

2. 12 - 2.62

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12
Q

ext Cl-

A

100 mM

95-105

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13
Q

ext HCO3-

A

25 mM

22-29

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14
Q

ext H+

A

40 nM

pH = 7.4

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15
Q

int Na+

A

5-15 mM

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16
Q

int K+

A

140 mM

17
Q

int Ca 2+

A

0.1 micromolar (um)

18
Q

int Cl-

A

less than extracellular but big range

19
Q

int HCO3-

A

10-20 mM

20
Q

int H+

A

50-100 nM

21
Q

daily sodium intake

A

max recommended = 2.4g

22
Q

daily intake

A

less than 3.6 g /day

23
Q

estimated daily sodium loss

A

23 mg

24
Q

plasma osmolarity

A

290 mOsM

25
Q

urine osmolarity

A

30-1200 mOsM

26
Q

pH calc

A

-log10[H+]

27
Q

normal pH values

A
[H+] = 40nM 
pH = 7.4
28
Q

defence against alkalosis and acidosis

A

buffers
ventilatory mechanisms
renal mechanisms

29
Q

use of Henderson hasselbalch equation

A

estimate the pH of a buffer solution

30
Q

Henderson Hasselbalch equation

A

pH = Pka + log10 [A-]/[HA]

A- = conjugate base 
HA = weak acid
31
Q

main intracell buffer

A

haemoglobin

can also have some proteins and phosphate

32
Q

main extracell buffer

A

carbonic anhydrase/ bicarbonate
albumin
ammonia

33
Q

buffer concept

A

can resist changes in ph when small amounts of acid or base are added