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Clinical Chem Snoopy style > Body Fluids > Flashcards

Body Fluids Flashcards

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1
Q

What are some functions of CSF?

A

Physical support/protection
control environment/remove waste
transport

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2
Q

T/F CSF usually is done with a lumbar puncture around L3/L4

A

true, it is usually clear and colorless

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3
Q

What is the order of tubes?

A

1 chem
2 micro
3 heme
4 extra

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4
Q

Describe xanthochromia

A

yellow color due to an older bleed

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5
Q

How do you distingush between a traumatic tap and hemorrhage

A

amount of blood
clot presense
centrifuge

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6
Q

What are some biochemical markers

A

glucose, protein, lactate, glutamine
(centrifuge samples)

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7
Q

Describe Glucose in CSF
what type of transport
how many hours prior

A

facillitate transport downhill
2-4 hrs prior
increased is not clinically significant >600

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8
Q

Descrease glucose causes what disorders

A

disorders in metabolism carriers
ex. bacteria/tumors

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9
Q

T/F: Consumption of glucose decreases lactate and anerobic glycolysis

A

false, increases lactate and anaerobic glycolysis

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10
Q

Protein in CSF
whatkind of infiltrate

Decrease of Protein is caused by ___

Increased protein caused by ___

A

selective ultra infiltrate + serum analysis

Dec of prt: dialysis
protein loss
leakage

Incr Prt: lysis of contam blood
permeability
obstruction

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11
Q

T/F: Leakage ID of CSF is used with B- transferrin and CSF and more preAlB than serum

A

true

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12
Q

T/F: the blood brain barrier is less permeable from bacteria and is diagnostic of infections w meningitis

A

false, it is more permeable with bacteria and not diagnostic of meningitis

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13
Q

Can ALB cross the BBB?
IgG?

What is the value for intact BBB

A

Yes, it can cross the bbb,
IgG can not

intact BBB is <9

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14
Q

What is the IgG index used for? what is its range?

A

Index used for diagnosis of demyelinating diseases like MS
<0.73

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15
Q

T/F: CSF electrophoresis is used for suspected MS

A

true

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16
Q

T/F: Increase serum ALB = Icreased CSF levels

A

true

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17
Q

Describe lactate
what kind of metabolism
increased lactate does what/what disease
time critical thing

A

anaerobic metabolism
increased lactate dec glucose = meningitis
sodium fluoride time critical

18
Q

Describe Glutamine
increaed in what disease

A

ammonia and glutamate increased in hepatic encephalopathy

19
Q

Describe serous fluid
location
membranes
what type of infiltrate

A

heart/lungs/abdominal cavitites
2 serous membranes
Parietal = wall
visceral = lines organs
ultrainfiltrate

20
Q

Describe where pleural
pericardia
and peritoneal is

A

pleural - lungs
pericard - heart
periton - abdominal

21
Q

Describe the formation of serous fluids

A

continuous hydrostatic pressure/oncotic pressure

22
Q

Describe Effusion

A

accum of serious fluids (too much)

23
Q

Describe transudate

A

systemic disorder distrupts fluid filtration

24
Q

Describe exudates

A

occurs with inflamation and damage to walls

25
Q

Describe pleural fluids
locations (paretal/viseral)
how much fluid

transudates
exudates

A

systemic (paretal)
bronchial (viseral)
3-20ml of fluid

Transudates: secondary to remote
Exudates: primary imm. attention/damage

26
Q

Describe a thoracentesis

A

removal of pleural fluids
pH <7.2 infection
6.0 esophogus rupture

27
Q

T/F Uric acid is high in exudates

A

false it is low

28
Q

Describe pericardial fluid

A

similar to lungs
effusions around the heart and almost always EXUDATES
<50ml of fluid

29
Q

Describe Peritoneal fluid
how much is disease
excess is called
what is the primary

A

> 50ml disease
excess fluid = ascities
primary is exudates
untrasounds

30
Q

In peritoneal fluid, what is the transudate/exudates

neuts >250…

A

transudate - portal hypertension >1.1
exudates: prostates

neuts >250 peritonitis

31
Q

Amnoic fluids

A

surrounds fetus
production/clearance
transudation across fetal skin

32
Q

T/F: aminocentisis is with ultrasound

A

true

33
Q

Describe hemolytic disease of the fetus

A

incompatitble fetal/maternal blood (rH type)

34
Q

Describe neural tube defects

A

alpha fetal protein
Multiple of median

35
Q

Describe Fetal lung maturity

A

prevents lung collapse
steroids given
PG/lecthin (L/S RATIO)

36
Q

Describe lamellar body counts:

A

phospholipids produced by alveolar cells >50,000 good <15,000 bad

37
Q

T/F PG is preformed with C/S ratio

A

true

38
Q

Describe Sweat
greater than what to repeat

A

cystic fibrosis only test
>60 + repeat
affected by hydration

39
Q

Describe synovial fluids

A

moveabel joints
mucoprotein hyaluronic acid
rarely more than 3ml
Add hyaluronidase

40
Q

What is total protein of Synovial fluids
fasting

A

1-3g/dL

fasting- 6-8 hrs 10mg lower than serum

41
Q

T/F: uric acid is used to rule out gout

A

true
6-8mg/dl

42
Q

T/F: Lactice acid is usually <25mg/dL
1000 is septic arthritis

A

true

Clinical Chem Snoopy style (8 decks)

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