BODY DEFENSES Flashcards
Two mechanisms that make up the immune system
Innate and Adaptive defense systems
specific resistance to disease
Immunity
True or False. Immune system is a functional system rather than an organ system in an anatomical sense
True
What is the first line of defense?
Surface membrane barriers
Forms mechanical barrier that prevents entry of pathogens and other harmful substances into the body
Intact skin
Skin secretions make epidermal surface acidic, which inhibits bacterial growth; sebum also contains bacteria-killing chemicals
Acid mantle
Provides resistance against acids, alkalis, and bacterial enzymes.
Keratin
Form mechanical barrier that prevents entry of pathogens
Intact Mucous Membranes
Traps microorganisms in respiratory and digestive tracts.
Mucus
Filter and trap microorganisms and other airborne particles in nasal passages.
Nasal hairs
Propel debris-laden mucus away from lower respiratory passages
Cilia
Contains concentrated hydrochloric acid and protein-digesting enzymes that destroy pathogens in the stomach
Gastric juice
Inhibits growth of bacteria and fungi in female reproductive tract.
Acid mantle of vagina
Continuously lubricate and cleanse eyes and oral cavity
Tears and Saliva
What is the second line of defense?
Cellular and Chemical defenses
Engulf and destroy pathogens that breach surface membrane barriers; macrophages also contribute to immune response.
Phagocytes
Promote cell lysis by direct cell attack against virus-infected or cancerous body cells; do not depend on specific antigen recognition
Natural Killer Cells
Prevents spread of injurious agents to adjacent tissues, disposes of pathogens and dead tissue cells, and promotes tissue repair
Inflammatory Response
Group of plasma proteins that lyses microorganisms, enhances phagocytosis by opsonization, and intensifies inflammatory response.
Complement
Proteins released by virus-infected cells that protect uninfected tissue cells from viral takeover; mobilize the immune system
Interferons
Normally acid pH inhibits bacterial growth; urine cleanses the lower urinary tract as it flushes from the body.
Fluids with acid pH
Systemic response triggered by pyrogens; high body temperature inhibits multiplication of bacteria and enhances body repair processes
Fever