BM transplant

Question 1

Autologous BM transplant

Answer 1

Patient’s own SCs

Question 2

Allogenic

Answer 2

HLA-matched donor SCs

Question 3

Patient’s own SCs
BM eradicated with high dose chemo + radio to get rid of malignant cells
Mature cell malignancies (e.g. MM, lymphoma)
No GVHD + lower infection risk

Answer 3

Autologous transplant

Question 4

HLA-matched donor SCs
BM eradicated
More primitive malignancies when own HSCs more likely to be affected (leukaemia, AA)
GVHD risk, infections, infertility, secondary malignancy

Answer 4

Allogenic transplant