Blood vessels 1 Flashcards
What are the storage organelles for vWF?
Weibel-Palade bodies in ECs
Subtype of arteriosclerosis involving fibro-fatty plaques forming on intima
atherosclerosis
Subtype of arteriosclerosis involving calcification in the media of muscular arteries especially radial/ulnar
Monckeberg medial sclerosis
Hyaline thickening of small arteries due to essential HTN or DM
Hyaline arteriosclerosis
Onion skinning of artery in malignant HTN
Hyperplastic arteriosclerosis
Subtype of arteriosclerosis affecting elastic arteries and large muscular arteries. Spares pulmonary artery.
Atherosclerosis
Oxidation of LDL results in
foam cells
release of growth factors
endotheliotoxicity
Cells that secrete toxins which oxidize LDL
Macrophages
Microbes associated with infections in atherosclerosis
CMV, herpesvirus, chlamydia
Precursor lesion of atherosclerosis and present as early as newborns
fatty streaks
No clinical significance, p
lipid filled macrophages
foam cells
The basic lesion consists of central core of lipids covered by white fibrous cap
atheroma
Atheroma complication that induces thrombosis
rupture and ulceration of atheroma
Atheroma complication producing microemboli
cholesterol embolization of atheroma
Disease of aging (arteries)
Monckeberg medial sclerosis
Arteriosclerosis subtype that does not produce obstruction
Monckeberg
Monckeberg Media Muscular