Blood vessels 1 Flashcards

1
Q

What are the storage organelles for vWF?

A

Weibel-Palade bodies in ECs

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2
Q

Subtype of arteriosclerosis involving fibro-fatty plaques forming on intima

A

atherosclerosis

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3
Q

Subtype of arteriosclerosis involving calcification in the media of muscular arteries especially radial/ulnar

A

Monckeberg medial sclerosis

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4
Q

Hyaline thickening of small arteries due to essential HTN or DM

A

Hyaline arteriosclerosis

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5
Q

Onion skinning of artery in malignant HTN

A

Hyperplastic arteriosclerosis

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6
Q

Subtype of arteriosclerosis affecting elastic arteries and large muscular arteries. Spares pulmonary artery.

A

Atherosclerosis

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7
Q

Oxidation of LDL results in

A

foam cells
release of growth factors
endotheliotoxicity

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8
Q

Cells that secrete toxins which oxidize LDL

A

Macrophages

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9
Q

Microbes associated with infections in atherosclerosis

A

CMV, herpesvirus, chlamydia

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10
Q

Precursor lesion of atherosclerosis and present as early as newborns

A

fatty streaks

No clinical significance, p

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11
Q

lipid filled macrophages

A

foam cells

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12
Q

The basic lesion consists of central core of lipids covered by white fibrous cap

A

atheroma

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13
Q

Atheroma complication that induces thrombosis

A

rupture and ulceration of atheroma

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14
Q

Atheroma complication producing microemboli

A

cholesterol embolization of atheroma

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15
Q

Disease of aging (arteries)

A

Monckeberg medial sclerosis

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16
Q

Arteriosclerosis subtype that does not produce obstruction

A

Monckeberg

Monckeberg Media Muscular

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17
Q

Subtype of arteriosclerosis associated with benign HTN

A

hyaline arteriosclerosis

18
Q

Pipestem arteries

A

Monckeberg

19
Q

Subtype of arteriosclerosis associated with onion-skin arterioles

A

hyperplastic arteriosclerosis

20
Q

Subtype of arteriosclerosis associated with fibrinoid necrosis

A

hyperplastic arteriosclerosis

21
Q

Subtype of arteriosclerosis associated with nephrosclerosis

A

hyaline arteriosclerosis

22
Q

Subtype of arteriosclerosis associated with renal problems

A

hyaline arteriosclerosis

23
Q

Subtype of arteriosclerosis associated with scleroderma

A

hyperplastic arteriosclerosis

24
Q

Subtype of arteriosclerosis associated with renal problems

A

hyaline arteriosclerosis

25
Q

Subtype of arteriosclerosis which is more common in blacks than whites

A

hyaline arteriosclerosis

26
Q

Large spherical aneurysm

A

saccular

27
Q

Double-barreled aorta is a result of

A

aortic dissection

28
Q

This causes weakening of the aorta through vasa vasorum

A

syphilitic aneurysm

29
Q

Aneurysm caused by infection

A

mycotic

30
Q

Aneurysm caused by blood separating the layers of the blood vessel wall

A

aortic dissection

31
Q

Aneurysm found at circle of Willis has this shape

A

berry

32
Q

Associated with cystic medial degeneration

A

aortic dissection

33
Q

Where are abdominal aortic aneurysms usually found

A

below renal a, above iliac a bifurcation

34
Q

Causes obstruction of coronary ostia (root)

A

syphilitic aneurysm

35
Q

Pulsatile mass with back pain and severe abdominal pain could indicate:

A

imminent rupture of abdominal aortic aneurysm

36
Q

Tear creating false longitudinal lumen

A

aortic dissection (this is just a different way to describe)

37
Q

Proteases responsible for degradation of ECM, causing familial aneurysms

A

matrix metalloproteinases MMP

38
Q

Tearing chest pain radiating to the back and downwards

A

aortic dissection

39
Q

Tree-barking of aorta

A

syphilitic aneurysm

40
Q

A ruptured berry aneurysm forms what kind of brain hemorrhage?

A

subarachnoid

41
Q

False cysts replacing normal elastic tissue observed in

A

aortic dissection