Blood vessels 1 Flashcards

1
Q

What are the storage organelles for vWF?

A

Weibel-Palade bodies in ECs

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2
Q

Subtype of arteriosclerosis involving fibro-fatty plaques forming on intima

A

atherosclerosis

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3
Q

Subtype of arteriosclerosis involving calcification in the media of muscular arteries especially radial/ulnar

A

Monckeberg medial sclerosis

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4
Q

Hyaline thickening of small arteries due to essential HTN or DM

A

Hyaline arteriosclerosis

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5
Q

Onion skinning of artery in malignant HTN

A

Hyperplastic arteriosclerosis

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6
Q

Subtype of arteriosclerosis affecting elastic arteries and large muscular arteries. Spares pulmonary artery.

A

Atherosclerosis

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7
Q

Oxidation of LDL results in

A

foam cells
release of growth factors
endotheliotoxicity

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8
Q

Cells that secrete toxins which oxidize LDL

A

Macrophages

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9
Q

Microbes associated with infections in atherosclerosis

A

CMV, herpesvirus, chlamydia

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10
Q

Precursor lesion of atherosclerosis and present as early as newborns

A

fatty streaks

No clinical significance, p

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11
Q

lipid filled macrophages

A

foam cells

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12
Q

The basic lesion consists of central core of lipids covered by white fibrous cap

A

atheroma

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13
Q

Atheroma complication that induces thrombosis

A

rupture and ulceration of atheroma

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14
Q

Atheroma complication producing microemboli

A

cholesterol embolization of atheroma

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15
Q

Disease of aging (arteries)

A

Monckeberg medial sclerosis

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16
Q

Arteriosclerosis subtype that does not produce obstruction

A

Monckeberg

Monckeberg Media Muscular

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17
Q

Subtype of arteriosclerosis associated with benign HTN

A

hyaline arteriosclerosis

18
Q

Pipestem arteries

A

Monckeberg

19
Q

Subtype of arteriosclerosis associated with onion-skin arterioles

A

hyperplastic arteriosclerosis

20
Q

Subtype of arteriosclerosis associated with fibrinoid necrosis

A

hyperplastic arteriosclerosis

21
Q

Subtype of arteriosclerosis associated with nephrosclerosis

A

hyaline arteriosclerosis

22
Q

Subtype of arteriosclerosis associated with renal problems

A

hyaline arteriosclerosis

23
Q

Subtype of arteriosclerosis associated with scleroderma

A

hyperplastic arteriosclerosis

24
Q

Subtype of arteriosclerosis associated with renal problems

A

hyaline arteriosclerosis

25
Subtype of arteriosclerosis which is more common in blacks than whites
hyaline arteriosclerosis
26
Large spherical aneurysm
saccular
27
Double-barreled aorta is a result of
aortic dissection
28
This causes weakening of the aorta through vasa vasorum
syphilitic aneurysm
29
Aneurysm caused by infection
mycotic
30
Aneurysm caused by blood separating the layers of the blood vessel wall
aortic dissection
31
Aneurysm found at circle of Willis has this shape
berry
32
Associated with cystic medial degeneration
aortic dissection
33
Where are abdominal aortic aneurysms usually found
below renal a, above iliac a bifurcation
34
Causes obstruction of coronary ostia (root)
syphilitic aneurysm
35
Pulsatile mass with back pain and severe abdominal pain could indicate:
imminent rupture of abdominal aortic aneurysm
36
Tear creating false longitudinal lumen
aortic dissection (this is just a different way to describe)
37
Proteases responsible for degradation of ECM, causing familial aneurysms
matrix metalloproteinases MMP
38
Tearing chest pain radiating to the back and downwards
aortic dissection
39
Tree-barking of aorta
syphilitic aneurysm
40
A ruptured berry aneurysm forms what kind of brain hemorrhage?
subarachnoid
41
False cysts replacing normal elastic tissue observed in
aortic dissection