Blood Transfusion Flashcards
How are ABO groups decided?
ABO gene
What is coded for by the A gene?
N-acetyl-glycosaminotransferase
What is coded for by the B gene?
Galactose
What is the O antigen?
Isn’t one
It’s missing/non-functioning
What genes decide the Rh group?
RhD
RhCD
Which Rh gene is deleted and in what group of people?
RhD
Caucasians
Leads to Rh negative
What is the indication for a red cell transfusion?
Severe acute anaemia
Massive haemorrhage
Sickle cell
What blood is given as immediate transfusion?
O-
What should be done if blood is needed urgently but not immediately?
ABO and Rh status match
What should be done if blood is needed but not urgently?
Full cross match with other allo-antibodies
What is the indication for platelet transfusion?
Massive haemorrhage
Bone marrow failure
Surgery prophylaxis
What platelet levels should be aimed for in massive haemorrhage?
> 75
What platelet levels should be aimed for in bone marrow failure?
> 15
What platelet levels should be aimed for in minor surgery?
> 50
What platelet levels should be aimed for in major surgery?
> 75