blood transfusion

Question 1

what is the difference with FFP donation as opposed to red cel donation ?

Answer 1

FFP groups can only get from a group that has any of the same groups as them

Question 2

what is screened for in blood donors ?

Answer 2

sex
age
travel
tattoos
tested for ABO and Rh
screened for Hep B/C/E, HIV, syphillis

Question 3

what are indications for red cell transfusion ?

Answer 3

correct severe acute anaemia which might otherwise cause organ damage
improve QOL in uncorrectable anaemia
prepare patient for surgery/speed up recovery
reverse damage caused by own cells - sickle cell

Question 4

what are features of red cell storage/infusion ?

Answer 4

stored at 4 degrees
transfuse over 2-4 hours
1 unit increments 5g/l

Question 5

what are features of platelet storage and infusion ?

Answer 5

stored at -22 degrees
shelf life 7 days
transfuse over 20-30 mins

Question 6

when is platelet transfusion indicated ?

Answer 6

massive haemorrhage
bone marrow failure
prophylaxis for surgery
cardiopulmonary bypass

Question 7

when is FFP transfusion indicated ?

Answer 7

massive haemorrhage
DIC with bleeding
prophylactic

Question 8

what is Coombs test ?

Answer 8

red cells mixed with auto-antibody to test for autoimmunity

Question 9

what does a direct Coombs test indicate ?

Answer 9

autoimmune haemolytic anaemia
passive anti-D
haemolytic transfusion reaction

Question 10

what is haemolytic disease of fetes and newborn HDFN ?

Answer 10

RhD positive fetus, RhD negative mother

mother produces anti-D antibodies which cross placenta

Question 11

how do you prevent HDFN ?

Answer 11

prophylactic anti-D to sensitise mother