Blood Transfusion Flashcards

1
Q

What are the two main blood group classifications?

A

ABO blood group
Rh blood group

Both are based on the presence or absence of glycoproteins on RBC surfaces

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2
Q

What are the main points of blood group A concerning RBC transfusion?

A
  • Have A antigens
  • Have B antibodies
  • Can receive blood group groups A and O
  • Can donate to blood group A and AB
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3
Q

What are the main points of blood group B concerning RBC transfusion?

A
  • Have B antigens
  • Have A antibodies
  • Can receive blood from group B and O
  • Can give blood to groups B and AB
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4
Q

What are the main points of group AB regarding RBC transfusion?

A
  • Have A and B antigens
  • Have no antibodies
  • Can receive blood from groups A, B, AB and O
  • Can donate to group AB only
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5
Q

What is group AB known as?

A

Universal RBC recipient (can receive blood from any ABO blood group)

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6
Q

What are the main points of blood group O?

A
  • Have no antigens
  • Have A and B antibodies
  • Can receive blood from group O
  • Can give blood to groups A, B, AB and O
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7
Q

What is group O known as?

A

Universal RBC donor

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8
Q

What can Rh positive blood recipients receive?

A

Rh positive OR negative blood since they don’t have antibodies against the Rh glycoprotein

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9
Q

What can Rh negative blood groups receive?

A

ONLY Rh negative blood

OR they might develop a haemolytic transfusion

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10
Q

When can Rh positive blood be given to Rh negative patients?

A

In emergencies - because Rh negative patients don’t automatically have anti D antibodies, this requires exposure.

It just means you couldn’t give them Rh positive blood again or they would have antibodies ready to produce the haemolytic transfusion syndrome.

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11
Q

What type of antibodies are A and B?

A

IgM

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12
Q

Who can group A give Fresh frozen plasma to?

A

Group A and group O

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13
Q

Who can group B give fresh frozen plasma to?

A

Group B and group O

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14
Q

Who can group AB give fresh frozen plasma to?

A

Group A, B, AB and O.

Universal FFP donors.

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15
Q

Who can group O give fresh frozen plasma to?

A

group O

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16
Q

Which type of antibody is anti D?

A

IgG

17
Q

What adverse reaction can occur in transfusions?

A

Haemolytic transfusion reaction

18
Q

What is done when someone is donating blood>

A

the first plug is put into a diversion pouch because that’s where most of the bacteria is

19
Q

How long should you transfuse RBCs over?

A

2-4hrs

20
Q

How long should you transfuse platelets over?

A

20-30mins

21
Q

When should you transfuse RBCs?

A

Severe acute anaemia
prepare patient for surgery
speed up recovery
reverse damage caused by a patients own RBCs (sickle cell disease)

22
Q

When should you transfer platelets?

A

Massive haemorrhage
Bone marrow failure (biggest use)
Prophylaxis for surgery
Cardiopulmonary Bypass

23
Q

Which tests can be done before transfusing a patient?

A

Coombs test