Blood Products Flashcards
What are the ABO compatibility? (antigen and antibodies)
Anti=antibodies
O - no antigens, anti A anti B
A - A antigen, and anti B
B - A antigen, and anti A
AB - AB antigen, and no antibodies
Where are the antigens and antibodies?
Antigen is on the RBC (like the identifiers)
and
Antibodies in the plasma
What happens if there is no compatibility?
Hemolysis
What is Rh (D)?
Anti D antibodies develop in Rh- patients only when exposed to Rh+ RBC (Risk during pregnancy)
What is the Rh Compatibility?
Rh+ - D antigen, no anti D antibodies
Rh- - No D antigen, no anti D antibodies
(Unless exposed to D antigen, then creates anti D)
Antigen and anti are opposite letters, if same then hemolysis/not compatible
Which Blood can give and which can get?
Type Get Give
O+ +/- O (+)O,A,B,AB
O- -O all
A+ +/-A,O (+)A,AB
A- -A,-O A,AB
B+ +/-B,O (+)B,AB
B- -B,-O B,AB
AB+ all +AB
AB- (-)AB,A,B,O AB
What is Packed RBC (PRBC)?
It is 45% blood
Given d/t acute/chronic blood loss
Or hemoglobin <70
Must Pretest: group B screening q72hrs and crossmatch
What is Fresh Frozen Plasma (FFP)?
It is 55% blood
Given d/t bleeding
Prior to operative procedure
DIC, massive transfusion (from significant loss)
Pre-transfusion testing: ABO + type on current admission (Rh not considered on admission)
What are platelets blood products?
Given for thrombocytopenia or bleeding/massive transfusion
Pre transfusion testing: ABO group & Rh type
What are albumin blood products?
5% or 25% concentrations
Helps with fluid shifting
Given for
- Spontaneous bacteria peritonitis
- Large volume paracentesis (>5L) (draining from abdomen)
- Hepatorenal syndrome
- Volume replacement in therapeutic plasma exchange
NO PRETRANFUSION TESTING
What is Cryoprecipitate blood products?
Give for
- Acquired hypofibrinogenemia and bleeding
- <1.5 Fibrinogen level
- Factor XIII replacement when low
Pretransfusion testing: ABO group& RH type during admission
