Blood pressure Flashcards

1
Q

Outline the differences between series and parallel blood flow

A

series: 2 paths in a row, flow is the same in both, the pressure is higher in the first path than the second.
parallel: branching paths, flow is split, the pressure is the same at the start and both have identical resistance.

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2
Q

Define stroke volume

A

The volume of blood pumped out of the ventricle during one beat of the heart

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3
Q

Define heart rate

A

measured in beats per min

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4
Q

Define cardiac output and what is the equation

A

The volume of blood pumped out of a ventricle per min

CO= HR*SV

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5
Q

What is the end-diastolic volume

A

the volume of blood in a ventricle at the end of diastole, associated with preload.

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6
Q

What is the end-systolic volume

A

the volume of blood remaining in a ventricle at the end of systole. SV: EDV-ESV

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7
Q

What is the ejection fraction

A

The percentage of filled ventricular volume pumped out during a heartbeat: SV/EDV

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8
Q

What is the effect of a smaller radius in blood vessels

A

it increases resistance and leads to a lower flow rate

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9
Q

What is the effect of exercise on blood pressure

A

peripheral vasodilatation: muscle/skin
vasoconstriction: splanchnic circulation (gut)
BP: systolic (increase), diastolic (decrease), HR increases

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10
Q

Describe how endothelial cells achieve vasodilatation

A

Releases nitric oxide which causes the smooth muscle to relax and leads to vasodilatation.

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11
Q

Outline autonomic control of BP

A

Baroreceptors located in the transverse aortic arch detect BP which relay the information to the medulla that acts to increase or decrease HR, PR, pressure, CO.

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12
Q

Outline the Frank-Starling mechanism

A

The stroke volume of the heart increases in response to an increase in the stretching of blood filling the heart (EDP)

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13
Q

define venous return

A

the rate of blood flowing back to the heart through the veins

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14
Q

define preload

A

The initial stretching of the cardiomyocytes during diastole, dependant on venous return

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15
Q

What is volume overload

A

Results when preload becomes too large

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16
Q

State some factors affecting preload

A

Atrial contractility, HR, aortic pressure, ventricular compliance, central venous pressure.

17
Q

What is afterload

A

The resistance that the chambers of the heart must overcome to eject blood out of the heart. Pressure in LV compared to the aortic valve.

18
Q

What is the thoracic pump

A

Pulls the blood (from below) towards the right atrium, during inspiration.

19
Q

What is the muscle pump

A

Rhythmic contractions of limb muscles due to normal locomotor activity squeezes blood out of nearby veins towards the heart.

20
Q

hypertension

A

due to high BP, often asymptomatic and can lead to CAD and MI

21
Q

What can chronic hypertension lead to

A

Kidney failure, HF, cardiac hypertrophy, MI and aneurysm or stroke.

22
Q

Orthostatic hypertension

A

low bp on standing, dizziness or syncope, causes include drugs, hypovolaemia and age.