Blood Physiology Flashcards

1
Q

connective tissue that consists of cells & cell fragments surrounded by a liquid matrix

A

Blood

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2
Q

blood contributes ________% of the body weight

A

8

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3
Q

liquid matrix in the blood

A

plasma

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3
Q

component of blood that is 45% the total

A

formed elements

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4
Q

RBC is how many % of the formed elements of blood?

A

95

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5
Q

WBC is how many % of the formed elements of blood?

A

4-5

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6
Q

Platelets are how many % of the formed elements of blood?

A

<1

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7
Q

Other component of blood consisting of the remaining 55%

A

Plasma

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8
Q

H2O is ___ % of plasma

A

91

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9
Q

Proteins are ____ % of plasma

A

7%

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10
Q

most abundant plasma protein

A

albumin

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11
Q

percentage of albumin in plasma

A

58%

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12
Q

function of albumin

A

protein transport

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13
Q

percentage of globulin in plasma

A

38%

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14
Q

percentage of fibrinogen in plasma

A

48%

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15
Q

function of fibrinogen

A

clotting factor

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16
Q

Normal RBC count in males

A

5.2 - 6.5 million/mm3

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17
Q

Normal RBC count in females

A

4.5 - 5.5 million/mm3

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18
Q

Normal Hgb count in males

A

13 - 18 g/dL

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19
Q

Average normal Hgb count in males

A

16 g/dL

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20
Q

Normal Hgb count in females

A

12 - 16 g/dL

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21
Q

Average normal Hgb count in females

A

14 g/dL

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22
Q

term used to identify percentage of RBC in the blood

A

hematocrit

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23
Q

Normal Hct value in males

A

42 - 52%

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24
Q

Normal Hct value in females

A

37 - 47%

25
Q

Hallmark for inflammation

A

erythrocyte sedimentation rate

26
Q

Normal ESR value in males

A

< 15 mm/h

27
Q

Normal ESR value in females

A

<25 mm/h

28
Q

Normal WBC count

A

5,000 - 10,000 /mm3

29
Q

Normal platelet count

A

150,000 - 350,000 /mm3

30
Q

Normal bleeding time

A

1 - 6 minutes

31
Q

Normal clotting time

A

6 - 10 minutes

32
Q

Hct value that would render contraindication to exercise

A

<27%

33
Q

Hgb value that would render contraindication to exercise

A

<8 g/dL

34
Q

WBC count that would render contraindication to exercise

A

<5,000 /mm3

35
Q

Platelet count that would render contraindication to exercise

A

<20,000 /mm3

36
Q

type of exercise done for platelet count within 20,000-50,000

A

light exercise

37
Q

function of RBC

A

transport oxygen

38
Q

lifespan of RBC

A

120 days

39
Q

characteristics of RBC

A

biconcave disc, (-) nucleus, (+) Hgb, pliable

40
Q

function of Hgb

A

the actual oxygen carrier

41
Q

All formed elements in the blood are derived from

A

pluripotential hematopoietic stem cell

42
Q

other term for PHSC

A

hemocytoblast

43
Q

process of RBC formation

A

Erythropoiesis

44
Q

hormone that stimulates production of RBC

A

erythropoietin

45
Q

origin of erythropoietin (include %)

A

kidney (90%), liver (10%)

46
Q

1st stage of RBC formation
(PoBRE)

A

proerythroblast

47
Q

2nd stage of RBC formation;
1st generation cell in RGB formation where the cell starts to acquire Hgb

(PoBRE)

A

basophil erythroblast

48
Q

3rd stage of RBC formation:
- (+) ejection of nucleus

(PoBRE)

A

reticulocytes

49
Q

4th stage of RBC formation
(PoBRE)

A

Erythrocyte

50
Q

producer of RBC during 1st trimester

A

yolk sac

51
Q

producers of RBC during 2nd trimester

A

liver, thymus, spleen, lymph nodes

52
Q

produces of RBC during 3rd trimester until p birth

A

bone marrow

53
Q

factors that increase RBC formation

__Hint__: BATCH

A

Bone marrow disease
Altitude is higher
Tissue hypoxia
Circulatory disease
Hemorrhage

54
Q

Vitamin that causes pernicius anemia if absent.

A

Vit B12

55
Q

other name for vit B12

A

cyanocobalamin

56
Q

also known as Vit B9

A

folic acid

57
Q

Vit B12 and Vit B9 are best absorbed where?

A

ileum

58
Q

vitamin responsible for Hgb synthesis

A

iron

59
Q

Fe is best absorbed in _______

A

duodenum