Blood, Lymphatic & Immune System - Pathologies Flashcards

1
Q

Acquired Immunity

A

Immunity developed over time through exposure to specific pathogens or vaccines. It involves the production of antibodies and memory cells, allowing the body to respond more effectively to future infections.

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2
Q

Adaptive Immunity

A

A specialized branch of acquired immunity that includes B cells and T cells, which recognize and remember specific antigens, leading to a stronger immune response upon subsequent exposures.

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3
Q

Adenoids

A

A cluster of lymphatic tissue located in the upper part of the throat behind the nasal cavity, playing a role in trapping and filtering harmful pathogens before they enter the body.

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4
Q

Agranulocyte

A

A type of white blood cell that lacks granules in its cytoplasm, such as lymphocytes (B and T cells) and monocytes, which are crucial for immune function and response.

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5
Q

Antigen

A

Any foreign substance, such as bacteria, viruses, or toxins, that triggers an immune response, leading to the production of specific antibodies by the immune system.

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6
Q

Apheresis

A

A medical procedure where specific components of blood (such as plasma, platelets, or white blood cells) are separated and removed, while the rest of the blood is returned to the body. This is used for conditions like leukemia or autoimmune diseases.

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7
Q

Aplastic Anemia

A

A rare but serious blood disorder in which the bone marrow fails to produce enough red blood cells, white blood cells, and platelets, leading to fatigue, infections, and excessive bleeding.

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8
Q

Appendix

A

A small, finger-like organ attached to the large intestine, which was once thought to be vestigial but is now believed to play a role in gut immunity and the maintenance of beneficial gut bacteria.

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9
Q

B Cell (B Lymphocyte)

A

A type of white blood cell responsible for producing antibodies in response to pathogens. Some B cells become memory B cells, which enable a quicker immune response upon future exposure to the same pathogen.

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10
Q

Basophil

A

A type of white blood cell containing granules filled with histamine and other chemicals that are released during allergic reactions and inflammation. They help initiate the immune response to allergens and parasites.

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11
Q

Blood Transfusions

A

The transfer of blood or blood components (such as red blood cells, plasma, or platelets) from a donor to a recipient, often used in cases of severe blood loss, anemia, or clotting disorders.

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12
Q

Bone Marrow

A

The soft, spongy tissue inside bones that produces blood cells, including red blood cells (RBCs), white blood cells (WBCs), and platelets through a process called hematopoiesis.

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13
Q

Cytotoxic T Cell (Killer T Cell)

A

A subtype of T cell that directly attacks and destroys virus-infected cells, cancer cells, and other harmful invaders by releasing toxic enzymes.

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14
Q

Eosinophil

A

A type of white blood cell involved in allergic reactions and the defense against parasitic infections, particularly helminths (parasitic worms). Elevated eosinophil counts often indicate an allergic reaction or parasitic infection.

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15
Q

Erythroblast

A

An immature red blood cell found in the bone marrow that develops into a mature erythrocyte after shedding its nucleus.

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16
Q

Erythrocyte (Red Blood Cell - RBC)

A

A type of blood cell responsible for carrying oxygen throughout the body using hemoglobin. RBCs are produced in the bone marrow and have a lifespan of about 120 days.

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17
Q

Fibrin

A

A fibrous protein that plays a key role in blood clotting. When an injury occurs, fibrin forms a mesh-like structure to stop bleeding by trapping blood cells and forming a clot.

18
Q

Granulocyte

A

A category of white blood cells that contain granules in their cytoplasm, including neutrophils, eosinophils, and basophils. These cells play a role in the immune response by attacking pathogens.

19
Q

Helper T Cell

A

A type of T cell that coordinates the immune response by stimulating B cells to produce antibodies and activating cytotoxic T cells to kill infected cells.

20
Q

Hematocrit

A

A measurement of the percentage of red blood cells in total blood volume. A low hematocrit level can indicate anemia, while a high level can indicate dehydration or polycythemia.

21
Q

Hematopoietic Stem Cell

A

A type of stem cell found in the bone marrow that can differentiate into any type of blood cell, including red blood cells, white blood cells, and platelets.

22
Q

Hemolysis

A

The destruction of red blood cells, which releases hemoglobin into the bloodstream. This can occur due to infections, autoimmune disorders, or incompatible blood transfusions.

23
Q

Hemophilia

A

A genetic disorder in which the blood does not clot properly due to a deficiency in clotting factors, leading to excessive bleeding even from minor injuries.

24
Q

Inflammatory Response

A

The body’s natural reaction to injury or infection, characterized by redness, swelling, heat, and pain. It involves the release of immune chemicals such as histamine and cytokines.

25
Q

Leukemia

A

A type of cancer affecting the blood and bone marrow, characterized by an overproduction of abnormal white blood cells that crowd out normal cells, leading to anemia, infections, and bleeding problems.

26
Q

Lymph

A

A clear, watery fluid that circulates through the lymphatic system, carrying white blood cells, waste, and other substances to help remove infections and maintain fluid balance.

27
Q

Lymphocyte

A

A type of white blood cell involved in immune responses. It includes B cells (antibody production), T cells (cell-mediated immunity), and natural killer (NK) cells (which kill virus-infected and cancer cells).

28
Q

Macrophage

A

A large white blood cell that engulfs and digests pathogens, dead cells, and debris in a process called phagocytosis. Macrophages also help activate other immune cells.

29
Q

Monocyte

A

A type of white blood cell that circulates in the blood and differentiates into macrophages or dendritic cells once it enters tissues, playing a key role in the immune response.

30
Q

Mononucleosis

A

A viral infection caused by the Epstein-Barr virus (EBV), leading to fever, sore throat, swollen lymph nodes, and extreme fatigue.

31
Q

Natural Immunity (Innate Immunity)

A

The body’s first line of defense against infections, involving physical barriers (skin, mucous membranes) and non-specific immune responses like phagocytes and natural killer cells.

32
Q

Natural Killer (NK) Cells

A

A type of lymphocyte that attacks and destroys virus-infected cells and cancer cells without prior sensitization.

33
Q

Neutrophil

A

The most abundant type of white blood cell and a key player in the innate immune system, responsible for rapidly responding to infections by engulfing bacteria and fungi.

34
Q

Pathogen

A

A microorganism that causes disease, such as bacteria, viruses, fungi, and parasites.

35
Q

Pernicious Anemia

A

A type of anemia caused by a vitamin B12 deficiency, which leads to improper red blood cell formation and neurological symptoms.

36
Q

Plasma

A

The liquid portion of blood, composed mostly of water, proteins, hormones, and waste products, which transports nutrients and immune cells throughout the body.

37
Q

Platelet (Thrombocyte)

A

A small, disc-shaped cell fragment that plays a key role in blood clotting and wound healing by forming a temporary plug at the site of an injury.

38
Q

Rheumatoid Arthritis (RA)

A

A chronic autoimmune disorder in which the immune system mistakenly attacks the joints, causing pain, inflammation, and deformity.

39
Q

Sickle Cell Anemia

A

A genetic disorder in which red blood cells take on a sickle (crescent) shape, leading to blockages in blood flow and reduced oxygen delivery to tissues.

40
Q

Spleen

A

An organ that filters blood, removes old or damaged red blood cells, and helps the immune system by producing lymphocytes and storing platelets.

41
Q

T Cells (T Lymphocytes)

A

A type of white blood cell that plays a crucial role in cell-mediated immunity, including helper T cells, cytotoxic T cells, and regulatory T cells.

42
Q

Thalassemia

A

A genetic blood disorder characterized by abnormal hemoglobin production, leading to severe anemia.