Blood images Flashcards
Neutrophilic bands are characterized by further constriction of the nucleus causing it to
have the shape of a curved rod. The chromatin is condensed, and the cytoplasm resembles that of a
mature neutrophil.
Neutrophilic bands are characterized by further constriction of the nucleus causing it to
have the shape of a curved rod. The chromatin is condensed, and the cytoplasm resembles that of a
mature neutrophil.
Neutrophil
unusual nuclei that consist of 2-5 lobes that are attached to one another by fine threads of chromatin
cytoplasm appears a salmon-pink color in a Romanovsky stained blood smear
salmon pink and reddish purple grnaules
This cell has a weird nucleus, as you know: it has hot-dog-link segments with pinched, narrowed strands of nucleus between the segments
neutrophil
EOSINOPHILS
same size as neutrophils
large, spherical, eosinophilic granules.
nucleus of eosinophils is typically bilobed
The granules in eosinophils are beautiful – they are large, luminous, and reddish-orange. The word eosin comes from the Greek word eos, which means “flush of the dawn sky.
The nucleus is nothing to write home about, really – it’s segmented into a few different parts, and it looks kind of like a neutrophil nucleus.
EOSINOPHILS
same size as neutrophils
large, spherical, eosinophilic granules.
nucleus of eosinophils is typically bilobed
EOSINOPHILS
same size as neutrophils
large, spherical, eosinophilic granules.
nucleus of eosinophils is typically bilobed
BASOPHILS
the cell with the big, super-dark-purple-blue granules
The granules are so numerous and dark that they often obscure the nucleus
large cytoplasmic granules that stain intensely with azure Band appear a deep violet
same size as
neutrophils and eosinophils.
Basophil nuclei are irregular in shape but less segmented than those of the other granulocytes.
BASOPHILS
it’s the cell with the big, super-dark-purple-blue granules
The granules are so numerous and dark that they often obscure the nucleus
large cytoplasmic granules that stain intensely with azure Band appear a deep violet
same size as
neutrophils and eosinophils.
Basophil nuclei are irregular in shape but less segmented than those of the other granulocytes.
BASOPHILS
it’s the cell with the big, super-dark-purple-blue granules (
large cytoplasmic granules that stain intensely with azure Band appear a deep violet
same size as
neutrophils and eosinophils.
Basophil nuclei are irregular in shape but less segmented than those of the other granulocytes.
SMALL/MEDIUM LYMPHOCYTE
intensely staining, spherical nucleus surrounded by a thin rim of pale blue cytoplasm.
The medium lymphocyte is about 8-10 µm in diameter. Its cytoplasm is more abundant, and its nucleus is larger and less heterochromatic than that of the small
lymphocyte.
SMALL/MEDIUM LYMPHOCYTE
intensely staining, spherical nucleus surrounded by a thin rim of pale blue cytoplasm.
The medium lymphocyte is about 8-10 µm in diameter. Its cytoplasm is more abundant, and its nucleus is larger and less heterochromatic than that of the small
lymphocyte.
LARGE LYMPHOCYTE
The large lymphocyte is about 10-18 µm in diameter. Its nucleus is even less heterochromatic than that of the medium lymphocyte.
In some large lymphocytes one can also
observe azurophilic granules within their cytoplasm. These are the natural killer (NK) cells.
LARGE LYMPHOCYTE
The large lymphocyte is about 10-18 µm in diameter. Its nucleus is even less heterochromatic than that of the medium lymphocyte.
In some large lymphocytes one can also
observe azurophilic granules within their cytoplasm. These are the natural killer (NK) cells.
bottom is a
small/medium lymphocyte
Large granular lymphocyte ( NK cell )
2 neutrophils and 1 Large granular lymphocyte ( NK cell )
Monocyte
Monocytes have a horseshoe-shaped nucleus, with dishwater-gray cytoplasm and a few tiny granules.
abundant, bluish grey cytoplasm with a dusty appearence due to grnaules. also can sometimes see vacuoles.
nucleus of a monocyte can be
almost any shape
The chromatin of a monocyte is
quite euchromatic.
Monocyte
Monocytes have a horseshoe-shaped nucleus, with dishwater-gray cytoplasm and a few tiny granules.
abundant, bluish grey cytoplasm with a dusty appearence due to grnaules. also can sometimes see vacuoles.
nucleus of a monocyte can be
almost any shape
The chromatin of a monocyte is
quite euchromatic.
platelets
small, non-nucleated cytoplasmic fragments of megakaryocytes. They
are disk-like bodies with a diameter of only 2-4 µm.
Blasts (myeloblasts)
The cytoplasm
appears pale blue, and there will be NO GRANULES present. A blast has a LARGE NUCLEOPLASMATIC ratio.
relatively large cells, from 10-15 µm in diameter.
The nucleus of a
blast is large and euchromatic, and several nucleoli can often be observed within it.
Blasts (myeloblasts)
The cytoplasm
appears pale blue, and there will be NO GRANULES present. A blast has a LARGE NUCLEOPLASMATIC ratio.
relatively large cells, from 10-15 µm in diameter.
The nucleus of a
blast is large and euchromatic, and several nucleoli can often be observed within it.
on left
left - blast
right - small/medium lymphocyte
Neutrophilic promyelocytes
spherical nuclei in which the chromatin is a little bit
more condensed than that of blasts. Nucleoli can often be observed
The cytoplasm of these cells is characterized by the presence of large, azurophilic granules (primary granules).
Neutrophilic promyelocytes
spherical nuclei in which the chromatin is a little bit
more condensed than that of blasts. Nucleoli can often be observed
The cytoplasm of these cells is characterized by the presence of large, azurophilic granules (primary granules).
Neutrophilic promyelocytes
spherical nuclei in which the chromatin is a little bit
more condensed than that of blasts. Nucleoli can often be observed
The cytoplasm of these cells is characterized by the presence of large, azurophilic granules (primary granules).
Neutrophilic myelocytes
have round or oval nuclei in which the chromatin will appear morecondensed than that of promyelocytes.
Small, SALMON- PINK GRANULES are now present in thE cytoplasm. These are the specific granules of neutrophils.
Neutrophilic myelocytes
have round or oval nuclei in which the chromatin will appear morecondensed than that of promyelocytes.
Small, SALMON- PINK GRANULES are now present in thE cytoplasm. These are the specific granules of neutrophils.
Neutrophilic myelocytes
have round or oval nuclei in which the chromatin will appear morecondensed than that of promyelocytes.
Small, SALMON- PINK GRANULES are now present in thE cytoplasm. These are the specific granules of neutrophils.
Neutrophilic metamyelocytes
indented nuclei that are quite condensed.
The
cytoplasm is dominated by the presence of numerous very small secondary (specific) granules.
cytoplasm the salmon-pink color that is typical of adult neutrophils.
Neutrophilic metamyelocytes
indented nuclei that are quite condensed.
The
cytoplasm is dominated by the presence of numerous very small secondary (specific) granules.
cytoplasm the salmon-pink color that is typical of adult neutrophils.
Neutrophilic bands
a further constriction of the nucleus causing it to
have the shape of a curved rod
. The chromatin is condensed, and the cytoplasm resembles that of a
mature neutrophil.
NEUTROPHILIC BAND
Neutrophil
BASOPHILE
Basophil nuclei are irregular in shape but less segmented than those of
the other granulocytes. This will be difficult for you to see because of the presence of large
cytoplasmic granules that usually obscure the nucleus. These granules stain intensely with azure B
and appear a deep violet in a typical blood smear.
Blasts (myeloblasts)
The nucleus of a
blast is large and euchromatic, and several nucleoli can often be observed within it. The cytoplasm
appears pale blue, and there will be no granules present. A blast has a large nucleocytoplasmic ratio.
are relatively large cells, from 10-15 µm in diameter.
Blasts (myeloblasts)
The nucleus of a
blast is large and euchromatic, and several nucleoli can often be observed within it. The cytoplasm
appears pale blue, and there will be no granules present. A blast has a large nucleocytoplasmic ratio.
are relatively large cells, from 10-15 µm in diameter.
Blasts (myeloblasts)
The nucleus of a
blast is large and euchromatic, and several nucleoli can often be observed within it. The cytoplasm
appears pale blue, and there will be no granules present. A blast has a large nucleocytoplasmic ratio.
are relatively large cells, from 10-15 µm in diameter.
Basophilic erythroblast (BE)
In addition, nuclear chromatin is more condensed.
Typically what you will see is a
speckled nucleus.
The cytoplasm of this cell will be intensely basophilic (navy blue)
There will be alternating areas of diffuse and compact chromatin, which gives the
nucleus a “checkerboard” appearance.
The nucleoli will often be obscured by the condensed
chromatin.
Basophilic erythroblasts are a bit smaller than blasts, and their nuclei are also smaller than
those of blasts.
Basophilic erythroblast (BE)
In addition, nuclear chromatin is more condensed.
Typically what you will see is a
speckled nucleus.
The cytoplasm of this cell will be intensely basophilic (navy blue)
There will be alternating areas of diffuse and compact chromatin, which gives the
nucleus a “checkerboard” appearance.
The nucleoli will often be obscured by the condensed
chromatin.
Polychromatophilic erythroblasts are even smaller cells, and their nuclei are more
condensed. Due to the accumulation of hemoglobin in these cells, their cytoplasm will display both
basophilia and eosinophilia at the same time. It will shift from blue gray to gray as the cell matures.
Frequently, polychromatophils cluster around reticular cells
Polychromatophilic erythroblasts are even smaller cells, and their nuclei are more
condensed. Due to the accumulation of hemoglobin in these cells, their cytoplasm will display both
basophilia and eosinophilia at the same time. It will shift from blue gray to gray as the cell matures.
Frequently, polychromatophils cluster around reticular cells
Normoblasts are smaller than polychromatophils. Their nuclei are also smaller and totally
condensed.
The cytoplasm of a normoblast is still faintly polychromatophilic (mostly pink with a
touch of blue).
Normoblasts are smaller than polychromatophils. Their nuclei are also smaller and totally
condensed.
The cytoplasm of a normoblast is still faintly polychromatophilic (mostly pink with a
touch of blue).
Orthochromatic erythroblasts (normoblast)
ose their residual RNA before they extrude their nuclei.
Therefore, this cell will have a small, heterochromatic nucleus surrounded by bright eosinophilic
cytoplasm.It will look just like a mature erythrocyte with asmall condensed nucleus. These cells
are normally not released into the peripheral circulation.
Orthochromatic normoblast
lose their residual RNA before they extrude their nuclei.
Therefore, this cell will have a small, heterochromatic nucleus surrounded by bright eosinophilic
cytoplasm. It will look just like a mature erythrocyte with a small condensed nucleus. These cells
are normally not released into the peripheral circulation.
Megakaryocyte
Megakaryoblasts are large cells with large polyploid nuclei. Their cytoplasm tends to be
basophilic. M
Megakaryocyte
Megakaryoblasts are large cells with large polyploid nuclei. Their cytoplasm tends to be
basophilic. M
lymphocyte
monocyte
eosinophil
small lymphocyte
large granular lymph
monocyte
blast (has several nuceloi – the vaucole looking things)
Neutrophilic promyelocyte (early)
myelocyte
Neutrophilic metamyelocyte
KIDNEY bean shaped
Basophilic erythroblast
“BEB” blue!
Polychromatophilic erythroblast
Orthochroma9c erythroblast
plasma cell
