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P Microanatomy 1 > Blood & Hematopoiesis > Flashcards

Blood & Hematopoiesis Flashcards

1
Q

What sps has sickle-shaped erythrocyte?

A

deer

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2
Q

What sps has thrombocytes that are nucleated?

A

Avian, reptiles, amphibians

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3
Q

Electrophoresis: what is A?

A

Albumin

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4
Q

What do basophil granules contain?

When would basophils increase?

A

histamine; w parasitic infection & allergic rxn

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5
Q

What is lymphopoiesis?

Where are they derived from?

A

lymphocyte maturation:

pluripotent stem cell to lymphoid stem cell to B or T lymphocyte

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6
Q

What are the 2 types of bone marrow?

A

Red Marrow

Yellow Marrow

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7
Q

What are the 3 functions of whole blood?

A

transport, temperature regulation, water blanace & blood vol

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8
Q

What is electrophoresis used for?

A

to separate proteins by electrocal charge & size

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9
Q

What is the most numerous wbc in the body?

A

neutrophil

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10
Q

What is the second most numerous cell in the blood?

A

lymphocyte

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11
Q

What are the 3 types of small lymphocytes?

A

B cells & T cells

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12
Q

What are the 3 granuolocytes?

A

neutrophils

eosinophils

basophils

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13
Q

What sps has a smaller erythrocytes w small or no central pallor?

A

Feline

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14
Q

What is a leukocyte?

What does it counteract?

A

white blood cell involved w counteracting foreign substrates & disease?

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15
Q

What is the process where specialized cellular processes devel into hightly differentiated cells of peripheral blood?

A

Hematopoiesis

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16
Q

What sps has a nucleated erythrocyte?

A

birds, reptiles, amphibians, fish

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17
Q

What is stroma?

What is it composed of?

A

CT network composed of mesenchymal cells, reticular cells, reticular fibers

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18
Q

What sps has ovoid erythrocyte?

A

Camalid

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19
Q

What does red marrow produce and what does it store?

A

all blood cells & stores iron

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20
Q

What is albumin’s role?

A

electron transport & maintians colloid oncotic pressure to keep fluid within blood

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21
Q

C What type of leukocyte has a large, dense nucleus w pale cytoplsam?

A

lymphocyte

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22
Q

What are the formed elements composed of?

A

Erythrocytes

Leukocytes

Thrombocytes

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23
Q

What is a erythrocyte?

What does it contian/carry?

A

Red blood cell containing hemoglobin which carries oxygen from lungs to tissues & CO2 from tissues to lungs

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24
Q

What is Monopoiesis?

What are they derived from?

A

monocyte maturation:

myeloid stem cell to monoblast to promonocyte to monocyte

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25
What is plasma mainly made up of? (3)
water, proteins, solutes
26
What is the most numerous cell in the body?
erythrocyte
27
What are heterophils? What do they contain?
neutrophils found in different sps that contain rice shaped granules that stain red
28
What sps has thrombocytes that are variable in size w well stained granules that are frequently activated?
Feline
29
Where are formed elements produced? What happens at the end of the life cycle?
produced by bone marrow & phagocytosed at end of life cycle
30
What percent of whole blood are formed elements?
40 %
31
Where does hematopoiesis postnatally take place?
bone marrow liver spleen specific bones
32
What percent of whole blood is plasma?
60%
33
What sps has smaller, irregular to spherical shaped erythrocyte?
Goats
34
**E** What type of leukocyte is large, has abundant purple granules in cytoplasm, and long ribbon-like nucleus?
basophil
35
Electrophoresis: what is B?
Inflammatory proteins
36
What are the two main types of leukocytes?
Granulocytes & Mononuclear cells
37
What is a monocyte? What is its role?
wbc that differentiates into macrophage for phagocytosis, for anitgen rpesenting to T cells, for iron storage
38
What type of immunity are neutrophils involved with?
innate immunity & phagocytosis
39
What is granulopoiesis? What are they derived from?
granulocyte maturation: myeloid stem cell to eosinophil or basophil OR to neutrophilic metamyelocyte to neutrophilic band to segmented nuetrophil
40
Where does hematopoiesis prenatally take place?
yolk sac liver spleen lymph nodes thymus bone marrow
41
What do neutrophil granules contain?
antibacterial substances
42
What is the function of eoinophils?
anti-bacertial & anti-parasitic
43
What is bone marrow derived from?
mesenchymal derived tissue
44
What is the difference btwn plasma & serum?
Plasma contains all proteins (need to use anticoagulant tubes) Serum contains NO coagulation proteins and NO fibrinogen
45
Where are B cells found? What type of immunity are they associated w?
in bone marrow, assocaited w humoral immunity
46
What are thrombocytes? What do they come from?
platelets; small anucleate discoid cytoplasmic fragments from megakaryocytes
47
Wherea re inflammatory proteins synthesized?
in the liver
48
What is the role of platelets?
hemostasis to produce blood clot & role in blood clot
49
**A** What type of leukocyte is larger than rbc's, has a pale cytoplsam, segmented nucleus, dense purple chromatin?
Neutrophil
50
Where are T cells found? What type of immunity are they associated with?
in thymus, for cell-mediated immunity
51
What sps has thrombocytes that are uniform in size & shape, have granules that are lightly stained?
Equine
52
What sps has thrombocytes that are small & numerous, some variation in size w densely stained granules?
Bovine
53
What percent of an animals body weight is whole blood?
~10%
54
What is it called to measure cells to give numeric counts per microliter of how many of a specific cell is present in the sample?
Complete Blood Count
55
What sps has a large erythrocyte w distinct central palor?
Canine
56
What is the least numerous wbc in the blood?
basophil
57
What is thrombopoiesis? What are they derived from?
platelet maturation: myeloid stem cell to megakaryoblast to prometakaryocyte to megakaryocyte to platelets
58
What are the two types of globulins?
inflammatory proteins & Immunoglobulins
59
Electrophoresis: what is C?
Immunoglobulins
60
What sps has this a smaller erythrocyte w no central pallor?
Equine
61
**B** What type of leukocyte is large, has a pale cytoplsam w red granules, & segmented nucleus?
Eosinophil
62
What is a plsama cell?
B cell
63
Why is plasma measured?
to monitor health of patient
64
**D** What type of leukocyte is large, has abundant blue vacuolated cytoplasm, variable shape nucleus w less dense chroamtin?
monocyte
65
What sps are heterophils found in?
rabbits, guinae pigs, birds, reptiles, amphibians
66
What are the 2 types of plasma proteins?
ablumin & globulins
67
What sps has thrombocytes that are variable in size w well stained granules?
Canine
68
What is erythropoiesis? What are they derived from?
rbc maturation: myeloid stem cell to metarubricyte to polychromatiphil to rbc
69
What sps has smaller erythrocyte w no central pallor?
Bovine
70
Electrophoresis: what is D?
Globulins
71
What are immunoglobulins produced by?
mature B cells (plasma cells)
72
When would abnormally nucleated rbc's appear? (4)
anemia, bone marrow damage, disease w rbc maturation, spleen damage
73
What is whole blood? What are the 2 parts?
special form of CT 1. formed elements 2. plasma (fluid matrix)
74
What is yellow marrow composed of? When does this type of bone marrow develop?
fatty tissue that replaces the res marrow when aging
75
What are the 3 mononuclear cells?
monocytes lymphocytes

P Microanatomy 1 (3 decks)

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