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P Microanatomy 1 > Blood & Hematopoiesis > Flashcards

Blood & Hematopoiesis Flashcards

1
Q

What sps has sickle-shaped erythrocyte?

A

deer

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2
Q

What sps has thrombocytes that are nucleated?

A

Avian, reptiles, amphibians

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3
Q

Electrophoresis: what is A?

A

Albumin

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4
Q

What do basophil granules contain?

When would basophils increase?

A

histamine; w parasitic infection & allergic rxn

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5
Q

What is lymphopoiesis?

Where are they derived from?

A

lymphocyte maturation:

pluripotent stem cell to lymphoid stem cell to B or T lymphocyte

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6
Q

What are the 2 types of bone marrow?

A

Red Marrow

Yellow Marrow

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7
Q

What are the 3 functions of whole blood?

A

transport, temperature regulation, water blanace & blood vol

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8
Q

What is electrophoresis used for?

A

to separate proteins by electrocal charge & size

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9
Q

What is the most numerous wbc in the body?

A

neutrophil

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10
Q

What is the second most numerous cell in the blood?

A

lymphocyte

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11
Q

What are the 3 types of small lymphocytes?

A

B cells & T cells

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12
Q

What are the 3 granuolocytes?

A

neutrophils

eosinophils

basophils

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13
Q

What sps has a smaller erythrocytes w small or no central pallor?

A

Feline

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14
Q

What is a leukocyte?

What does it counteract?

A

white blood cell involved w counteracting foreign substrates & disease?

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15
Q

What is the process where specialized cellular processes devel into hightly differentiated cells of peripheral blood?

A

Hematopoiesis

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16
Q

What sps has a nucleated erythrocyte?

A

birds, reptiles, amphibians, fish

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17
Q

What is stroma?

What is it composed of?

A

CT network composed of mesenchymal cells, reticular cells, reticular fibers

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18
Q

What sps has ovoid erythrocyte?

A

Camalid

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19
Q

What does red marrow produce and what does it store?

A

all blood cells & stores iron

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20
Q

What is albumin’s role?

A

electron transport & maintians colloid oncotic pressure to keep fluid within blood

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21
Q

C What type of leukocyte has a large, dense nucleus w pale cytoplsam?

A

lymphocyte

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22
Q

What are the formed elements composed of?

A

Erythrocytes

Leukocytes

Thrombocytes

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23
Q

What is a erythrocyte?

What does it contian/carry?

A

Red blood cell containing hemoglobin which carries oxygen from lungs to tissues & CO2 from tissues to lungs

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24
Q

What is Monopoiesis?

What are they derived from?

A

monocyte maturation:

myeloid stem cell to monoblast to promonocyte to monocyte

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25
Q

What is plasma mainly made up of? (3)

A

water, proteins, solutes

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26
Q

What is the most numerous cell in the body?

A

erythrocyte

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27
Q

What are heterophils?

What do they contain?

A

neutrophils found in different sps that contain rice shaped granules that stain red

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28
Q

What sps has thrombocytes that are variable in size w well stained granules that are frequently activated?

A

Feline

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29
Q

Where are formed elements produced?

What happens at the end of the life cycle?

A

produced by bone marrow & phagocytosed at end of life cycle

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30
Q

What percent of whole blood are formed elements?

A

40 %

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31
Q

Where does hematopoiesis postnatally take place?

A

bone marrow

liver

spleen

specific bones

32
Q

What percent of whole blood is plasma?

A

60%

33
Q

What sps has smaller, irregular to spherical shaped erythrocyte?

A

Goats

34
Q

E What type of leukocyte is large, has abundant purple granules in cytoplasm, and long ribbon-like nucleus?

A

basophil

35
Q

Electrophoresis: what is B?

A

Inflammatory proteins

36
Q

What are the two main types of leukocytes?

A

Granulocytes

&

Mononuclear cells

37
Q

What is a monocyte?

What is its role?

A

wbc that differentiates into macrophage for phagocytosis, for anitgen rpesenting to T cells, for iron storage

38
Q

What type of immunity are neutrophils involved with?

A

innate immunity & phagocytosis

39
Q

What is granulopoiesis?

What are they derived from?

A

granulocyte maturation:

myeloid stem cell to eosinophil or basophil

OR

to neutrophilic metamyelocyte to neutrophilic band to segmented nuetrophil

40
Q

Where does hematopoiesis prenatally take place?

A

yolk sac

liver

spleen

lymph nodes

thymus

bone marrow

41
Q

What do neutrophil granules contain?

A

antibacterial substances

42
Q

What is the function of eoinophils?

A

anti-bacertial & anti-parasitic

43
Q

What is bone marrow derived from?

A

mesenchymal derived tissue

44
Q

What is the difference btwn plasma & serum?

A

Plasma contains all proteins (need to use anticoagulant tubes)

Serum contains NO coagulation proteins and NO fibrinogen

45
Q

Where are B cells found?

What type of immunity are they associated w?

A

in bone marrow, assocaited w humoral immunity

46
Q

What are thrombocytes?

What do they come from?

A

platelets; small anucleate discoid cytoplasmic fragments from megakaryocytes

47
Q

Wherea re inflammatory proteins synthesized?

A

in the liver

48
Q

What is the role of platelets?

A

hemostasis to produce blood clot & role in blood clot

49
Q

A What type of leukocyte is larger than rbc’s, has a pale cytoplsam, segmented nucleus, dense purple chromatin?

A

Neutrophil

50
Q

Where are T cells found?

What type of immunity are they associated with?

A

in thymus, for cell-mediated immunity

51
Q

What sps has thrombocytes that are uniform in size & shape, have granules that are lightly stained?

A

Equine

52
Q

What sps has thrombocytes that are small & numerous, some variation in size w densely stained granules?

A

Bovine

53
Q

What percent of an animals body weight is whole blood?

A

~10%

54
Q

What is it called to measure cells to give numeric counts per microliter of how many of a specific cell is present in the sample?

A

Complete Blood Count

55
Q

What sps has a large erythrocyte w distinct central palor?

A

Canine

56
Q

What is the least numerous wbc in the blood?

A

basophil

57
Q

What is thrombopoiesis?

What are they derived from?

A

platelet maturation:

myeloid stem cell to megakaryoblast to prometakaryocyte to megakaryocyte to platelets

58
Q

What are the two types of globulins?

A

inflammatory proteins

&

Immunoglobulins

59
Q

Electrophoresis: what is C?

A

Immunoglobulins

60
Q

What sps has this a smaller erythrocyte w no central pallor?

A

Equine

61
Q

B What type of leukocyte is large, has a pale cytoplsam w red granules, & segmented nucleus?

A

Eosinophil

62
Q

What is a plsama cell?

A

B cell

63
Q

Why is plasma measured?

A

to monitor health of patient

64
Q

D What type of leukocyte is large, has abundant blue vacuolated cytoplasm, variable shape nucleus w less dense chroamtin?

A

monocyte

65
Q

What sps are heterophils found in?

A

rabbits, guinae pigs, birds, reptiles, amphibians

66
Q

What are the 2 types of plasma proteins?

A

ablumin

&

globulins

67
Q

What sps has thrombocytes that are variable in size w well stained granules?

A

Canine

68
Q

What is erythropoiesis?

What are they derived from?

A

rbc maturation:

myeloid stem cell to metarubricyte to polychromatiphil to rbc

69
Q

What sps has smaller erythrocyte w no central pallor?

A

Bovine

70
Q

Electrophoresis: what is D?

A

Globulins

71
Q

What are immunoglobulins produced by?

A

mature B cells (plasma cells)

72
Q

When would abnormally nucleated rbc’s appear? (4)

A

anemia, bone marrow damage, disease w rbc maturation, spleen damage

73
Q

What is whole blood?

What are the 2 parts?

A

special form of CT

  1. formed elements
  2. plasma (fluid matrix)
74
Q

What is yellow marrow composed of?

When does this type of bone marrow develop?

A

fatty tissue that replaces the res marrow when aging

75
Q

What are the 3 mononuclear cells?

A

monocytes

lymphocytes

P Microanatomy 1 (3 decks)

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