Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Blood Banking > Blood Group System > Flashcards

Blood Group System Flashcards

1
Q

ISBT #007

A

The Lewis system (Le)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The only major system not produced by RBCs. Intrinsic to GIT

A

Lewis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Ags are on type 1 glycosphingolipids

A

Lewis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Gene at chromosome 19 and codes for Gucosyltransferase 3

A

Lewis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Le (a+ b+) possible in

A

Asians

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

lele / Le (a- b-) / (Le^null) possible in

A

Blacks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Associated with Helicobacter pylori

A

Le^b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ISBT #002; Chromosome 4

A

MNS system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

• On glycophorin A
• amino acid #1 - serine
• amino acid # 5 - Glycine

A

M antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

• On glycophorin A
• amino acid #1 - Leucine
• amino acid # 5 - Glutamic acid

A

N antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

On glycophorin B
Amino acid #29 - Methionine

A

S antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

On glycophorin B
Amino acid #29 - Threonine

A

s antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Reaction enhanced at pH 6.5 (acidic)
Seen in multiparous women

A

Anti-M

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Reaction enhanced at alkaline pH
Seen in RENAL DIALYSIS patient where machine is sterilized with formaldehyde

A

Anti-N

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

ISBT # 003

A

P1PK

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Antigen that deteriorates rapidly upon storage. False nega in old specimen

A

P1 antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Neutralized by hydatid cysts fluid from E. Granulosus

A

Anti-P1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Found in fascioliasis

A

Anti-P1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Biphasic hemolysin

A

Autoanti-P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

_____ receptor for parvovirus19
_____ receptor for SHIGA TOXIN; cause HUS
_____ receptor for P-fambriated uropathogenic E. coli

A

P antigen
P^k antigen
P system antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

_____ hydatid cysts and other parasitic infection
_____ spontaneous abortions in Early pregnancy
_____ PCH

A

Anti-P1
Anti-Tja
Autoanti-P

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

ISBT#027

A

I (individual) system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Associated with HEMPAS or Chronic Dyserythropoietic Anemia II

A

I system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

HEMPAS

A

Hereditary Erythroblastic Multinuclearity with Positive Acidified Serum test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Most common agglutinin in patient with hemolytic anemia

A

Pathogenic Autoanti-I / Anti-I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Causes acrocyanosis

A

Anti-I / pathogenic Autoanti-I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Associated with congenital cataracts in Asians

A

Adult i

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Associated with:
IM
EBV infxn
Alcoholic Cirrhosis

A

Anti-i

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

ISBT#006; gene at chromosome 7

A

Kell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

First blood group to be discovered after antiglobulin testing

A

Kell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

ISBT#009; Chromosome 18

A

KIDD System

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Antigens of Kidd blood group

A
  • Jk (a+b-)
  • Jk (a+b+)
  • Jk (a-b+)
  • Jk (a-b-)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Antibodies of Kidd, Jk

A
  • Anti-Jk^a
  • Anti-Jk^b
  • Anti-Jk3
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Allen and colleagues (1951) reported finding antibody in the serum of Mrs. Kidd, whose infant (John Kidd) had HDFN

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Notorious in blood bank;

A

Anti-Jk^a
Anti-Jk^b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Can cause **severe immediate and delayed fatal HTR ** and mild HDFN

A

Anti-Jk3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Antihypertensive drugs that is associated with Drug induced HTR

A

Aldomet and Methyldopa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

ISBT #005; CHROMOSOME 19q

A

Lutheran System Lu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Jk(a+b-) seen in

A

Blacks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Jk(a-b+) and Jk (a+b+) seen in

A

Asians and Whites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Jk(a-b-) seen in

A

0.9% Polynesians
- Filipino
- Indonesians
- Japanese
- Chinese

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Lutheran Antigens

A
  • Lu^a
  • Lu^b
  • Lu3
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Lutheran antibodies

A
  • anti-Lu^a
  • anti-ALu^b
  • Anti-Lu^3
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Found in patient with SLE, RT reacting IgM and is naturally occurring
Clinically insignificant

A

Anti-Lu^a

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Associated with shortened survival of transfused cells and post transfusion jaundice(not severe)

A

Anti-Lu^b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

ISBT #010; Chromosome 17q

A

Diego system, Di

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Found in tissues like as brain, hepatocytes, lungs, pancreas, placenta, and skeletal muscle

A

Lu^a, Lu^b, and Lu3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Located on BAND-3 / ANION EXCHANGE-1(AE-1) or SLC4A1

A

Diego antigens
SLC4A1 - solute carrier family-4 anion exchanger, member 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Defects in AE-1 CAUSES

A

Congenital Acanthocytosis
Hereditary Spherocytosis
Southeast Asian Ovalocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Diego Antibodies

A

Anti-Di^a
Anti-Di^b
Anti-Wr^a
Anti-Wr^b

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q
  1. Anti-Di^a and -Di^b causes _______________
  2. Anti-Wr^a causes _______________
  3. Anti-Wr^b is relatively ________________
A
  1. HTRs and HDFN
  2. Severe HTR
  3. common in the serum of the patients with WAIHA
52
Q

ISBT #011; Chromosome 7q

A

Cartwright, Yt

53
Q

Located on Acetylcholine Esterase

A

Cartwright antigen
On GPI, GLYCOSYLPHOSPHATIDYLINOSITOL - linked RBC glycoprotein

54
Q

UYt antigens

A
  • Yt^a
  • Yt^b
55
Q

Yt antibodies

A
  • Anti-Yt^a
  • Anti-Yt^b
    Ab:IgG stimulated bypregnancy and transfusion
56
Q

ISBT #12; Chromosome X

A

Xg system

57
Q

ENHANCED by enzymes

A

KALIPR

  • Kidd
  • ABO
  • Lewis
  • I
  • P1
  • Rh
58
Q

UUNAFFECTED by enzyme

A

SKUL

  • Scianna
  • Kell
  • U
  • Lutheran
59
Q

DESTROYED by enzymes

A

DaMMn eX

  • Duffy
  • MNS
  • Xg^a
  • minor
    • JMH
    • Ch/Rg
    • Pr
60
Q

Mixed filled reaction

A
  • Sd^a
  • Lutheran
61
Q

Absent in PNH III

A
  • Dombrock
  • Cartwright
  • Cromer
  • JMH
62
Q

Antigens in
- saliva
- urine
- meconium

A

Sd^a

63
Q

Soluble form of Tamm-horsefall protein

A

UROMODULIN

64
Q

Antibody neutralized by urine

A

anti-Sd^a

65
Q

BennettGoodspeed Antigens

A

A.k.a. HUMAN LEUKOCYTE ANTIGENS

66
Q

Bg^a……….
Bg^b……….
Bg^c………..

A

Bg^a **HLA B7
Bg^b **HLA B17
Bg^c **HLA A28

67
Q

ISBT “022; CHROMOSOME 1q

A

Knops

68
Q

Located on Complement receptor 1 (CR1) or CD35

A

Knops

69
Q

Knops decreased in

A
  • **SLE
  • Coronary Artery Disease (CAD)**
70
Q

Phenotype of Knops null

A

HELGESON

71
Q

ISBT #023; Chromosome 11p

A

INDIAN

72
Q

In^a and In^b located in

A

CD44

73
Q

Chromosome 19p; ISBT #024

A

Ok system (Mr. Kabutso)

74
Q

Ok Antigens carried on

A

CD147

75
Q

Chromosome 11p; ISBT #025

A

Raph system

76
Q

Raph antigen

A

MER-2

77
Q

Raph located on

A

CD151

78
Q

Chromosome 15q; ISBT #026

A

John Milton Hagen JMH

79
Q

JMH antigens located on:

A

CDW108
SEMAPHORIN 7A

80
Q

Newest blood group
ISBT #030

A

RHAG

81
Q

Chromosome 6p

A
82
Q

Carbohydrate antigens

A

LIP

Lewis
I
P

83
Q

Poorly developed at birth

A

LLP

  • Lewis
  • Lutheran
  • P1
84
Q

Well developed at birth

A

DaMaK Ka

Duffy
MNSs
Kell
Kidd

85
Q

In Vito hemolysis

A

Anti-Le^a/ Anti-Le^b
Anti-Tja
Anti-Vel

86
Q

IgM antibodies

A

LIPBAHMN

LEWIS
I
P
B
A
M
N

87
Q

IgG antibodies

A

Rh
Kidd
Kell
Duffy
Lutheran
MNSs

88
Q

Decreased Ab in pregnancy (post-partum)

A

Le

89
Q

Neutralization

A

Anti-I/I : human breast milk
Anti-Sd^a Antibody : Guinea pig urine
Anti Ch/Rg : plasma/serum
Anti p1 Ab : hydatid cysts fluid, turtle dove’s egg whites, pigeon dropping

90
Q

Made by the Cromer null Inab phenotype

A

Anti-IFC

91
Q

Chromosome 1q; ISBT #021

A

Cromer

92
Q

Cromer antigens carried on

A

DAF *DK accelerating Factor
A.k.a. CD55

93
Q

Chromosome 2q; ISBT #020

A

Gerbich system

94
Q

Reacts with anti-AB and anti-B

A

B

95
Q

Mix filled reaction with anti-AB and anti-B

Most frequent B subtype

A

B3

96
Q

Weak reaction with anti-AB and anti-B

A

Bx

97
Q

No/weak reaction with anti-AB and anti-B

Converted to B if incubated with Uracil diphosphate

A

Bm

98
Q

No reaction with anti-AB and anti-B

Extremely rare phenotype

A

B el

99
Q

Anti-A1 lectin

A

Dolichos biflorus

100
Q

Anti-B lectin

A

Bandeiraea simplicifolia

Gniffonia simplicifolia

101
Q

Anti-H lectin

A

Ulex europaeus

102
Q

Anti-N lectin

A

Vicia graminea

103
Q

Anti-M lectin

A

Iberis amara

104
Q

Anti-T, Th lectin

A

Arachis hypogaea

105
Q

Anti-Tn lectin

A

Salvia sclarea

106
Q

Positive control in antisera QC

A

Ensures the Reactivityof the antisera

107
Q

Negative control in antisera QC

A

Ensures the Specificity of the antisera

108
Q

Higher frequency in females than males

A

Xg

109
Q

Associated withCD99

A.KA. **12E7 & MIC 2

A

Xg

110
Q

ISBT #013; Chromosome 1

A

Scianna

111
Q

Expressed on RBC adhesion protein called ERMAP

A

Scianna
Erythrocyte Membrane Associated Protein

112
Q

1% in northern Europeans but Higher in Mennonite population.

A

SC2

113
Q

Chromosome 12; ISBT #014

A

Dombrock

114
Q

Carried on ART-4

A

Dombrock
Mono-ADP Ribosylteansferase-4

115
Q

Associated with Renal disease

A

Raph antibody

116
Q

X-linked; located on the short arm of X chromosome

A

Xg

117
Q

Male- 66%
Female - 89%

A

Xg Ag

118
Q

Xg antibody

A

Anti - Xga

119
Q

ISBT#015; Chromosome 7p

A

Colton

120
Q

Antigens located on Aquaporin-1

A

Colton Ag

121
Q

Colton Antibodies

A

Anti-Co^a
Anti-Co^b

122
Q

ISBT #017; Chromosome 6p

A

Chido/Rogers

123
Q

Found on C4 complement

A

Ch/Rg Ag

124
Q

Nebulous Ag

A

Ch/Rg Ag

125
Q

Not intrinsic to RBCmembrane

A

Lewis and Ch/Rg Ags

Blood Banking (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions